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dc.contributor.author
Catalan, Cesar Atilio Nazareno
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dc.contributor.author
Sampietro, Diego Alejandro
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dc.contributor.other
Ákos Máthé
dc.contributor.other
Bandoni, Arnaldo Luis
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dc.date.available
2021-12-03T14:05:54Z
dc.date.issued
2021
dc.identifier.citation
Catalan, Cesar Atilio Nazareno; Sampietro, Diego Alejandro; Xenophyllum poposum (Philippi) V. A. Funk; Springer International Publishing; 2021; 525-535
dc.identifier.isbn
978-3030628178
dc.identifier.uri
http://hdl.handle.net/11336/148083
dc.description.abstract
Xenophyllum poposum (syn. Werneria poposa) is a cushion-forming creeping sub-shrub 3-5 cm tall with unpleasant smell, commonly known as poposa or pupusa and widely used in Andean traditional medicine to treat hypertension, altitude sickness (mountain sickness), hepatic diseases and digestive disorders such as intestinal inflammation, diarrhea, intestinal colic, rheumatism and indigestion. Mono- and sesquiterpenoids accompanied by benzofuran derivatives such as tremetone and 6-hydroxytremetone have been identified in its essential oil while p-hydroxyacetophenone and benzofuran derivatives, flavonoids, coumarins and diterpenoids were isolated from organic extracts of aerial parts. 4-Hydroxy-3-(isopenten-2-yl)-acetophenone (1) is by far the dominant component of the methanol extract along with minor amounts of 6-hydroxytremetone (2). The hypotensive effect of compounds 1 and 2 has been demonstrated in rats and mice. In addition to tremetone and 6-hydroxytremetone (2), several other essential oil components are also bioactive. Thus, T-cadinol (epi--cadinol) inhibits induced intestinal hypersecretion in mice and contractions of the isolated guinea pig ileum whilst T-cadinol and cadinol possess significant anti-inflammatory activity and inhibit nitric oxide production induced by lipopolisaccharides. All available information seems to support the uses of X. poposum in traditional medicine. Due to the presence of so many bioactive metabolites, strong effects should be expected after the consumption of this herb and, consequently, the amount consumed (dose) should be carefully controlled to avoid undesirable effects. It is desirable to conduct deeper research to chemically characterize this plant with precision and define quality parameters and chemotypes. Almost nothing is known on the water soluble metabolites of poposa and studies in this area are to be expected.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer International Publishing
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
AROMATIC PLANTS
dc.subject
MEDICINAL PLANTS
dc.subject
Xenophyllum poposum
dc.subject.classification
Biotecnología Agrícola y Biotecnología Alimentaria
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dc.subject.classification
Biotecnología Agropecuaria
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dc.subject.classification
CIENCIAS AGRÍCOLAS
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dc.title
Xenophyllum poposum (Philippi) V. A. Funk
dc.type
info:eu-repo/semantics/publishedVersion
dc.type
info:eu-repo/semantics/bookPart
dc.type
info:ar-repo/semantics/parte de libro
dc.date.updated
2021-09-01T13:52:40Z
dc.journal.pagination
525-535
dc.journal.pais
Suiza
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dc.journal.ciudad
Cham
dc.description.fil
Fil: Catalan, Cesar Atilio Nazareno. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán; Argentina
dc.description.fil
Fil: Sampietro, Diego Alejandro. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán; Argentina
dc.conicet.paginas
558
dc.source.titulo
Medicinal and aromatic plants of South America: Argentina, Chile and Uruguay
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