Intrinsic Disorder in the human papillomavirus E7 protein

Abstract

Papillomaviruses (PVs) are a group of small, nonenveloped, double-stranded DNA viruses, which infect the skin and mucous epithelia of reptiles, birds, and mammals, and have recently been classified as a separate virus family, the Papillomaviridae. To date, over 200 types have been identified, including more than 100 types that infect humans. PVs have a narrow host range, and many virus types can infect a single host species. The virion particles are 50–55 nm in diameter and have T7 icosahedral symmetry.