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dc.contributor.author
Arzeni, Carolina
dc.contributor.author
Pilosof, Ana Maria Renata
dc.date.available
2021-11-25T06:43:42Z
dc.date.issued
2019-08
dc.identifier.citation
Arzeni, Carolina; Pilosof, Ana Maria Renata; Bioaccessibility of folic acid in egg white nanocarriers and protein digestion profile in solution and in emulsion; Elsevier Science; LWT - Food Science and Technology; 111; 8-2019; 470-477
dc.identifier.issn
0023-6438
dc.identifier.uri
http://hdl.handle.net/11336/147385
dc.description.abstract
The objective of this work is to assess bioaccessibility of folic acid in egg white (EW) nanocarriers after digestion of solutions and emulsions containing the vitamin-protein complexes. Furthermore, the influence of folic acid binding on the peptides profile after digestion is also evaluated. To this end an in vitro gastrointestinal digestion was performed and the pattern of digestion products was determined by high performance liquid chromatography. When folic acid was bound to nanocarriers, the vitamin peak area was approximately 80% lower than the one for folic acid alone. In emulsion, even less amount was detected. After digestion, no significant differences on folic acid peak areas were observed. Folic acid was released from nanocarriers after digestion, thus indicating that the vitamin would be bioaccessible in the site of absorption. Moreover, it was demonstrated by tricine-SDS-PAGE that folic acid binding induced a slight aggregation of proteins, although it did not alter the profile of peptides obtained after digestion. Binding of folic acid to nanocarriers proved to cause no negative effect on EW proteins digestibility. On the contrary, it seemed to slightly enhance their digestion. These nanocarriers would constitute an adequate system for the preservation, transport and target delivery of this bioactive.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BIOACCESSIBILITY
dc.subject
EGG WHITE
dc.subject
FOLIC ACID
dc.subject
NANOCARRIERS
dc.subject
PEPTIDES
dc.subject.classification
Otras Nanotecnología
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Nanotecnología
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Bioaccessibility of folic acid in egg white nanocarriers and protein digestion profile in solution and in emulsion
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-11-25T17:59:20Z
dc.journal.volume
111
dc.journal.pagination
470-477
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Arzeni, Carolina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Químicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Químicos; Argentina
dc.description.fil
Fil: Pilosof, Ana Maria Renata. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Químicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Químicos; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias; Argentina
dc.journal.title
LWT - Food Science and Technology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1016/j.lwt.2019.05.070
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0023643819304955