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dc.contributor.author
Carmona, Maximiliano
dc.contributor.author
Martín Giménez, Virna Margarita
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dc.contributor.author
Manucha, Walter Ariel Fernando
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dc.date.available
2021-11-05T11:39:20Z
dc.date.issued
2021-10
dc.identifier.citation
Carmona, Maximiliano; Martín Giménez, Virna Margarita; Manucha, Walter Ariel Fernando; Prevention and Treatment of Acute Respiratory Distress Syndrome by COVID-19: Role of Vitamin D on Immunomodulation and Renin-Angiotensin-Aldosterone System Regulation; Biomedical Research Network; Biomedical journal of scientific & technical research; 39; 3; 10-2021; 31419-31425
dc.identifier.uri
http://hdl.handle.net/11336/146086
dc.description.abstract
The leading cause of complications or death from COVID-19 is due to the development of acute respiratory distress syndrome (ARDS). This syndrome is characterized by exacerbated inflammation, mainly at the pulmonary level, and an over-activation of the renin-angiotensin-aldosterone system (RAAS), usually culminating in death or permanent respiratory sequelae in the SARS-CoV-2 infected patients. In this sense, it has been proposed that vitamin D exerts numerous immunomodulatory effects by acting on various types of immune and epithelial cells, as well as being able to stimulate the protective arm (ACE2/Ang-(1-7)) and inhibit the harmful arm (ACE/Ang-II) of the RAAS. Therefore, some of the main mechanisms underlying these effects mediated by vitamin D and its receptors are discussed in the present review. The analysis of these mechanisms would positively influence the prevention and treatment of ARDS, thus preventing the progression of the disease and improving the prognosis of the patients.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Biomedical Research Network
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
ACUTE RESPIRATORY DISTRESS SYNDROME
dc.subject
VITAMIN D
dc.subject
CYTOKIN STORM
dc.subject
PREVENTION
dc.subject
COVID-19
dc.subject.classification
Farmacología y Farmacia
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dc.subject.classification
Medicina Básica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Prevention and Treatment of Acute Respiratory Distress Syndrome by COVID-19: Role of Vitamin D on Immunomodulation and Renin-Angiotensin-Aldosterone System Regulation
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-11-03T14:56:23Z
dc.identifier.eissn
2574-1241
dc.journal.volume
39
dc.journal.number
3
dc.journal.pagination
31419-31425
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: Carmona, Maximiliano. Gobierno de la Provincia de Mendoza. Hospital Luis Lagomaggiore.; Argentina. Ministerio de Salud de la Nación; Argentina. Ministerio de Desarrollo Social; Argentina. Ministerio de Desarrollo Social. Secretaria de Deportes de la Nacion; Argentina
dc.description.fil
Fil: Martín Giménez, Virna Margarita. Universidad Catolica de Cuyo - Sede San Juan. Facultad de Ciencias de la Alimentación, Bioquímicas y Farmacéuticas. Instituto de Investigación en Ciencias Químicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; Argentina
dc.description.fil
Fil: Manucha, Walter Ariel Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Departamento de Patología; Argentina
dc.journal.title
Biomedical journal of scientific & technical research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.26717/BJSTR.2021.39.006314
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://biomedres.us/volume39-issue3.php
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