Artículo

Vicenin-2, a potential anti-inflammatory constituent of Urtica circularis

Marrassini, CarlaIcon ; Davicino, Roberto CarlosIcon ; Acevedo, Cristina; Anesini, Claudia AlejandraIcon ; Gorzalczany, Susana; Ferraro, Graciela EsterIcon
Fecha de publicación: 05/2011
Editorial: American Chemical Society
Revista: Journal of Natural Products
ISSN: 0163-3864
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Vicenin-2, a flavonoid glycoside, was isolated and identified from an ethanol extract of the aerial parts of Urtica circularis. This crude extract was found to possess significant anti-inflammatory activity in a carrageenan-induced rat hind paw edema model (41.5% inhibition at a dose of 300 mg/kg; ip). The effects of 1 on several inflammatory mediators were investigated. In cultured murine macrophages, this compound modified LPS-induced total nitrite and TNF-R production, in addition to the LPS-induced translocation of the nuclear factor NF-kB.
Palabras clave: Vicenin-2 , Antiinflammatory Activity , Urtica Circularis
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/14593
URL: http://pubs.acs.org/doi/abs/10.1021/np100937e
DOI: http://dx.doi.org/10.1021/np100937e
Colecciones
Articulos(IMIBIO-SL)
Articulos de INST. MULTIDICIPLINARIO DE INV. BIO. DE SAN LUIS
Citación
Marrassini, Carla; Davicino, Roberto Carlos; Acevedo, Cristina; Anesini, Claudia Alejandra; Gorzalczany, Susana; et al.; Vicenin-2, a potential anti-inflammatory constituent of Urtica circularis; American Chemical Society; Journal of Natural Products; 74; 6; 5-2011; 1503-1507
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