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dc.contributor.author
Estrada, Esteban
dc.contributor.author
Décima, Jose L.
dc.contributor.author
Rodríguez, Marcelo
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Di Tomaso, Marianela
dc.contributor.author
Roberti, Javier Eugenio
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dc.date.available
2021-10-27T11:19:00Z
dc.date.issued
2020-07
dc.identifier.citation
Estrada, Esteban; Décima, Jose L.; Rodríguez, Marcelo; Di Tomaso, Marianela; Roberti, Javier Eugenio; Patient-Reported Outcomes After Platelet-Rich Plasma, Bone Marrow Aspirate, and Adipose-Derived Mesenchymal Stem Cell Injections for Symptomatic Knee Osteoarthritis; SAGE Publications; Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders; 13; 7-2020; 1-4
dc.identifier.issn
1179-5441
dc.identifier.uri
http://hdl.handle.net/11336/145180
dc.description.abstract
Objective: The objective of this study was to compare platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), and adipose-derived mesenchymal stem cell (MSC) injections in the treatment of osteoarthritis (OA) of the knee using functional scores. Methods: A total of 89 patients with painful knee OA were included in this study. Patients were assigned to one of the 3 treatments according to severity of OA as indicated by symptoms and radiography to PRP (stage I), BMAC (stage II), or adipose-derived MSC (stage III). Clinical assessment was performed using the Knee Society Score, which combines the Knee Score, based on the clinical parameters, and the Functional Score, and IKDC score. Surveys were completed at preoperative and at 90, 180, and 265 days postoperative. The follow-up responses were compared with baseline and between treatment groups. Results: Treatment with PRP, BMAC, and adipose-derived MSC included 29 (32.6%), 27 (30.3%), and 33 (37.1%) patients, respectively. For the total group, median age was 61 years (range: 22-84 years). Score values were comparable among treatment groups at baseline. Statistically significant improvement was observed in the 3 groups according to the 3 scores at all time points during follow-up compared with baseline. No difference was found among treatment type. Conclusions: Our findings support previous reports and encourage further research on the use of these cost-effective treatments for OA of the knee.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
SAGE Publications
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.subject
ADIPOSE-DERIVED MESENCHYMAL STEM CELL
dc.subject
BONE MARROW ASPIRATE CONCENTRATE
dc.subject
KNEE
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OSTEOARTHRITIS
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PLATELET-RICH PLASMA
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Otras Ciencias de la Salud
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dc.subject.classification
Ciencias de la Salud
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Patient-Reported Outcomes After Platelet-Rich Plasma, Bone Marrow Aspirate, and Adipose-Derived Mesenchymal Stem Cell Injections for Symptomatic Knee Osteoarthritis
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-10-25T17:08:22Z
dc.journal.volume
13
dc.journal.pagination
1-4
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: Estrada, Esteban. Gobierno de la Provincia de San Luis. Hospital Policlinico Regional Juan Domingo Peron.; Argentina
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Fil: Décima, Jose L.. Gobierno de la Provincia de San Luis. Hospital Policlinico Regional Juan Domingo Peron.; Argentina
dc.description.fil
Fil: Rodríguez, Marcelo. Gobierno de la Provincia de San Luis. Hospital Policlinico Regional Juan Domingo Peron.; Argentina
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Fil: Di Tomaso, Marianela. Gobierno de la Provincia de San Luis. Hospital Policlinico Regional Juan Domingo Peron.; Argentina
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Fil: Roberti, Javier Eugenio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Gobierno de la Provincia de San Luis. Hospital Policlinico Regional Juan Domingo Peron.; Argentina
dc.journal.title
Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1177/1179544120931086
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