Artículo
IgY-technology (egg yolk antibodies) in human medicine: A review of patents and clinical trials
Leiva, Carlos Leónidas
; Gallardo, Mauro Julian
; Casanova, Natalia Andrea
; Terzolo, Horacio Raúl; Chacana, Pablo Anibal
Fecha de publicación:
04/2020
Editorial:
Elsevier Science
Revista:
International Immunopharmacology
ISSN:
1567-5769
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its cost-effective extraction, the minimization of animal harm and distress, and its reduced reactivity with mammalian factors. Many research groups have demonstrated that IgY is active against several pathogens or conditions, a fact that may support the design of novel, safe and effective health products. This review provides a comprehensive analysis of IgY-based biologicals for human medicine, including patent applications and clinical trials during the period 2010–2018, and addresses how IgY-technology can lead to innovation in the production of biologicals for the treatment and prophylaxis of a wide range of infectious and non-communicable diseases.
Palabras clave:
ANTIBODIES
,
CLINICAL TRIAL
,
EGG YOLK
,
IGY-TECHNOLOGY
,
PATENT
,
THERAPY
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos (IPVET)
Articulos de INSTITUTO DE PATOBIOLOGIA VETERINARIA
Articulos de INSTITUTO DE PATOBIOLOGIA VETERINARIA
Citación
Leiva, Carlos Leónidas; Gallardo, Mauro Julian; Casanova, Natalia Andrea; Terzolo, Horacio Raúl; Chacana, Pablo Anibal; IgY-technology (egg yolk antibodies) in human medicine: A review of patents and clinical trials; Elsevier Science; International Immunopharmacology; 81; 4-2020; 1-10
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