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dc.contributor.author
Danilovich, Mariana Elizabeth
dc.contributor.author
Alberto, Maria Rosa
dc.contributor.author
Juárez Tomás, María Silvina
dc.date.available
2021-10-15T03:48:15Z
dc.date.issued
2021-10
dc.identifier.citation
Danilovich, Mariana Elizabeth; Alberto, Maria Rosa; Juárez Tomás, María Silvina; Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health; Wiley Blackwell Publishing, Inc; Journal of Applied Microbiology; 131; 4; 10-2021; 1668-1682
dc.identifier.issn
1364-5072
dc.identifier.uri
http://hdl.handle.net/11336/143744
dc.description.abstract
Micro-organisms have showed the ability to produce biologically active compounds associated with neurotransmission in higher organisms. In particular, serotonin- and melatonin-producing microbes are valuable sources for the development of eco-friendly bioproducts. Serotonin and melatonin are indoleamines that have received special attention due to their positive effects on human health. These biomolecules exert a critical role in several physiological or pathological processes, including some mental and neurological disorders. This article includes a review of the microbial production of serotonin and melatonin, their functions in micro-organisms and their potential uses as therapeutic and/or preventive agents to improve human health. A description of the quantification methods employed to detect indoleamines and the evidence found concerning their microbial production at laboratory and industrial scale—for application in biotechnological products—is also provided. The microbial ability to synthesize beneficial indoleamines should be further studied and harnessed, to allow the development of sustainable bioprocesses to produce foods and pharmaceuticals for human health.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
BIOTECHNOLOGICAL PRODUCTS
dc.subject
HUMAN HEALTH
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INDOLEAMINES
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MICRO-ORGANISMS
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SEROTONIN AND MELATONIN BIOSYNTHESIS
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Biología Celular, Microbiología
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-06-10T19:23:59Z
dc.identifier.eissn
1365-2672
dc.journal.volume
131
dc.journal.number
4
dc.journal.pagination
1668-1682
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Danilovich, Mariana Elizabeth. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
dc.description.fil
Fil: Alberto, Maria Rosa. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
dc.description.fil
Fil: Juárez Tomás, María Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
dc.journal.title
Journal of Applied Microbiology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/jam.15012
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/jam.15012
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