Artículo
Extended adaptive predictive controller with robust filter to enhance blood glucose regulation in type I diabetic subjects
Fecha de publicación:
06/2013
Editorial:
Pergamon-Elsevier Science Ltd
Revista:
Computers and Chemical Engineering
ISSN:
0098-1354
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
In this paper, an improved adaptive predictive control with robust filter is developed to be applied in anartificial pancreas. Several problems inherent to endocrine systems for diabetic persons have to be tackled such as nonlinearities, long time delays or daily variations of parameters. Three Finite Impulse Response models for insulin input and the same for meal intake (perturbations) corresponding to normal, hyper-hypoglycaemia levels to implement three zones control are taken into account. The glycaemia reference trajectory is shaped from a healthy person response. A variable weighting factor in the cost function is included to prevent dangerous glycaemia excursions out of the allowed limits. Additionally, a noisy blood glucose subcutaneous sensor model is used. This control strategy is tested on 30 virtual subjects from the UVa/Padova Simulator. Simultaneous meals and physiological disturbances are taken into accountand the main conclusions are drawn from Control Variability Grid Analysis.
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Articulos(CCT - ROSARIO)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - ROSARIO
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - ROSARIO
Articulos(CIFASIS)
Articulos de CENTRO INT.FRANCO ARG.D/CS D/L/INF.Y SISTEM.
Articulos de CENTRO INT.FRANCO ARG.D/CS D/L/INF.Y SISTEM.
Citación
Campetelli, Germán; Lombarte, Mercedes; Basualdo, Marta Susana; Rigalli, Alfredo; Extended adaptive predictive controller with robust filter to enhance blood glucose regulation in type I diabetic subjects; Pergamon-Elsevier Science Ltd; Computers and Chemical Engineering; 59; 6-2013; 243-251
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