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dc.contributor.author
Arias, Juan A.  
dc.contributor.author
Williams, Claire  
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Raghvani, Rashmi  
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Aghajani, Moji  
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Baez, Sandra  
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Belzung, Catherine  
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Booij, Linda  
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Busatto, Geraldo  
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Chiarella, Julian  
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Fu, Cynthia  
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Ibañez, Agustin Mariano  
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Liddell, Belinda J.  
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Lowe, Leroy  
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Penninx, Brenda W.J.H.  
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Rosa, Pedro  
dc.contributor.author
Kemp, Andrew H.  
dc.date.available
2021-10-14T14:56:31Z  
dc.date.issued
2020-04  
dc.identifier.citation
Arias, Juan A.; Williams, Claire; Raghvani, Rashmi; Aghajani, Moji; Baez, Sandra; et al.; The neuroscience of sadness: A multidisciplinary synthesis and collaborative review; Pergamon-Elsevier Science Ltd; Neuroscience and Biobehavioral Reviews; 111; 4-2020; 199-228  
dc.identifier.issn
0149-7634  
dc.identifier.uri
http://hdl.handle.net/11336/143577  
dc.description.abstract
Sadness is typically characterized by raised inner eyebrows, lowered corners of the mouth, reduced walking speed, and slumped posture. Ancient subcortical circuitry provides a neuroanatomical foundation, extending from dorsal periaqueductal grey to subgenual anterior cingulate, the latter of which is now a treatment target in disorders of sadness. Electrophysiological studies further emphasize a role for reduced left relative to right frontal asymmetry in sadness, underpinning interest in the transcranial stimulation of left dorsolateral prefrontal cortex as an antidepressant target. Neuroimaging studies – including meta-analyses – indicate that sadness is associated with reduced cortical activation, which may contribute to reduced parasympathetic inhibitory control over medullary cardioacceleratory circuits. Reduced cardiac control may – in part – contribute to epidemiological reports of reduced life expectancy in affective disorders, effects equivalent to heavy smoking. We suggest that the field may be moving toward a theoretical consensus, in which different models relating to basic emotion theory and psychological constructionism may be considered as complementary, working at different levels of the phylogenetic hierarchy.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Pergamon-Elsevier Science Ltd  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/  
dc.subject
AFFECTIVE NEUROSCIENCE  
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BASIC EMOTIONS  
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GENETICS  
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GENIAL MODEL  
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HEALTH AND WELLBEING  
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HEART RATE VARIABILITY  
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MAJOR DEPRESSIVE DISORDER  
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NEUROIMAGING  
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PSYCHOLOGICAL CONSTRUCTIONISM  
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PSYCHOPHYSIOLOGY  
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SADNESS  
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VAGAL FUNCTION  
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Neurociencias  
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Medicina Básica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
The neuroscience of sadness: A multidisciplinary synthesis and collaborative review  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2021-09-07T19:14:51Z  
dc.journal.volume
111  
dc.journal.pagination
199-228  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Arias, Juan A.. Swansea University; Reino Unido. Universidad de Santiago de Compostela; España  
dc.description.fil
Fil: Williams, Claire. Swansea University; Reino Unido  
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Fil: Raghvani, Rashmi. Swansea University; Reino Unido  
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Fil: Aghajani, Moji. No especifíca;  
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Fil: Baez, Sandra. Universidad de los Andes; Colombia  
dc.description.fil
Fil: Belzung, Catherine. Universite de Tours; Francia  
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Fil: Booij, Linda. Concordia University Montreal; Canadá  
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Fil: Busatto, Geraldo. Universidade de Sao Paulo; Brasil  
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Fil: Chiarella, Julian. Concordia University Montreal; Canadá  
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Fil: Fu, Cynthia. University Of East London; Reino Unido  
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Fil: Ibañez, Agustin Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva y Traslacional. Fundación Ineco Rosario Sede del Incyt | Instituto de Neurología Cognitiva. Instituto de Neurociencia Cognitiva y Traslacional. Fundación Ineco Rosario Sede del Incyt | Fundación Favaloro. Instituto de Neurociencia Cognitiva y Traslacional. Fundación Ineco Rosario Sede del Incyt; Argentina. Universidad Adolfo Ibañez; Chile. Universidad Autónoma del Caribe; Colombia  
dc.description.fil
Fil: Liddell, Belinda J.. University of New South Wales; Australia  
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Fil: Lowe, Leroy. No especifíca;  
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Fil: Penninx, Brenda W.J.H.. No especifíca;  
dc.description.fil
Fil: Rosa, Pedro. Universidade de Sao Paulo; Brasil  
dc.description.fil
Fil: Kemp, Andrew H.. Universidade de Sao Paulo; Brasil. Swansea University; Reino Unido  
dc.journal.title
Neuroscience and Biobehavioral Reviews  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.neubiorev.2020.01.006  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0149763418306146?via%3Dihub