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dc.contributor.author
Molina, Rocío Daniela Inés
dc.contributor.author
Campos Silva, Rodrigo
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Díaz, Myriam Anabel
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Macedo, Alexandre José
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Blázquez, María Amparo
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Alberto, Maria Rosa
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Arena, Mario Eduardo
dc.date.available
2021-10-12T20:35:22Z
dc.date.issued
2020-12
dc.identifier.citation
Molina, Rocío Daniela Inés; Campos Silva, Rodrigo; Díaz, Myriam Anabel; Macedo, Alexandre José; Blázquez, María Amparo; et al.; Laurel extracts inhibit quorum sensing, virulence factors and biofilm of foodborne pathogens; Elsevier Science; LWT - Food Science and Technology; 134; 12-2020; 1-9; 109899
dc.identifier.issn
0023-6438
dc.identifier.uri
http://hdl.handle.net/11336/143339
dc.description.abstract
Antimicrobial, antibiofilm, anti-Quorum sensing (QS) and virulence factors inhibitory capacity of different polarity Laurus nobilis extracts against several pathogenic microorganisms were studied. Some extracts exhibited antibiotic effect against Staphylococcus aureus multidrug-resistant strains. However, all extracts (100 µg/mL) inhibited to some extent the biofilm of most bacteria tested (until 40% for Gram-negative and 76% for Gram-positive). Hexane (HE) and chloroform extract (CE) were potent inhibitors of S. aureus biofilm and the microscopies further confirmed an important reduction in adherent cells. Polystyrene surfaces coated with these extracts showed a decrease in bacterial adhesion with the resulting inhibition of S. aureus biofilm formation and biofilm activity. Moreover, they also interfere with the coagulase and hemolysin activities of this bacterium. With respect to Gram-negative bacteria, these extracts showed anti-QS activity against Chromobacterium violaceum and inhibited biofilm formation, swarming motility, pyocyanin production, and elastase activity of Pseudomonas aeruginosa. Chemical analysis of HE and CE revealed that the fatty acids were the main compounds, particularly linolenic, oleic and hexadecanoic acids followed by the oxygenated monoterpenes. Non-toxic laurel extracts offer a natural alternative to control contamination and/or spoilage of food, as well as infectious diseases, by attacking the biofilm and the virulence of Gram-positive and Gram-negative bacteria.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BIOFILM
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ENZYME INHIBITION
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FATTY ACIDS
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SWARMING
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PYOCYANIN
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Biología Celular, Microbiología
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Laurel extracts inhibit quorum sensing, virulence factors and biofilm of foodborne pathogens
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-07-01T13:52:53Z
dc.journal.volume
134
dc.journal.pagination
1-9; 109899
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Molina, Rocío Daniela Inés. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
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Fil: Campos Silva, Rodrigo. Universidade Federal do Rio Grande do Sul; Brasil
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Fil: Díaz, Myriam Anabel. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
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Fil: Macedo, Alexandre José. Universidade Federal do Rio Grande do Sul; Brasil
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Fil: Blázquez, María Amparo. Universidad de Valencia; España
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Fil: Alberto, Maria Rosa. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
dc.description.fil
Fil: Arena, Mario Eduardo. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
dc.journal.title
LWT - Food Science and Technology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1016/j.lwt.2020.109899
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0023643820308884