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dc.contributor.author
Gonzalez, Heidi Soledad
dc.contributor.author
Bloise, Leonardo
dc.contributor.author
Maza, Francisco Javier
dc.contributor.author
Molina, Fernando Víctor
dc.contributor.author
Delorenzi, Alejandro
dc.date.available
2021-10-06T19:29:31Z
dc.date.issued
2020-04
dc.identifier.citation
Gonzalez, Heidi Soledad; Bloise, Leonardo; Maza, Francisco Javier; Molina, Fernando Víctor; Delorenzi, Alejandro; Memory built in conjunction with a stressor is privileged: Reconsolidation-resistant memories in the crab Neohelice; Pergamon-Elsevier Science Ltd; Brain Research Bulletin; 157; 4-2020; 108-118
dc.identifier.issn
0361-9230
dc.identifier.uri
http://hdl.handle.net/11336/142955
dc.description.abstract
The dynamics of memory processes are conserved throughout evolution, a feature based on the hypothesis of a common origin of the high-order memory centers in bilateral animals. Reconsolidation is just one example. The possibility to interfere with long-term memory expression during reconsolidation has been proposed as potentially useful in clinical application to treat traumatic memories. However, several pieces of evidence in rodents show that either robust fear memories or stressful events applied before acquisition promote reconsolidationresistant memories, i.e., memories that are resistant to the interfering effect of drugs on memory reconsolidation. Conceivably, the generation of these reconsolidation-resistant fear memories also occurs in humans. Is the induction of reconsolidation-resistant memories part of the dynamics of memory processes conserved throughout evolution? In the semiterrestrial crab Neohelice granulata, memory reconsolidation is triggered by a short reminder without reinforcement. Here, we show that an increase in the salience of the aversive stimulus augmented the memory strength; nonetheless, the protein synthesis inhibitor cycloheximide still disrupted the reconsolidation process. However, crabs stressed by a water-deprivation episode before a strong training session built up a memory that was now reconsolidation-resistant. We tested whether these reconsolidation-resistant effects can be challenged by changing parametric conditions of memory-reminder sessions; multiple memory reactivations without reinforcement were not able to trigger the labilization-reconsolidation of this resistant memory. Overall, the present findings suggest that generation of reconsolidation-resistant memories can be another part of the dynamics of memory processes conserved throughout evolution that protects privileged information from change.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Pergamon-Elsevier Science Ltd
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
EVOLUTION
dc.subject
MEMORY
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MEMORY EXPRESSION
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RECONSOLIDATION
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RESISTANT MEMORIES
dc.subject
STRESS
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Otras Ciencias Biológicas
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Memory built in conjunction with a stressor is privileged: Reconsolidation-resistant memories in the crab Neohelice
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-09-07T18:43:48Z
dc.journal.volume
157
dc.journal.pagination
108-118
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Gonzalez, Heidi Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
dc.description.fil
Fil: Bloise, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
dc.description.fil
Fil: Maza, Francisco Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
dc.description.fil
Fil: Molina, Fernando Víctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Farmacología Experimental de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Farmacología Experimental de Córdoba; Argentina
dc.description.fil
Fil: Delorenzi, Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
dc.journal.title
Brain Research Bulletin
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0361923019308391
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.brainresbull.2020.01.014
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