Artículo
Camera-based CW diffuse optical tomography for obtaining 3D absorption maps by means of digital tomosynthesis
Carbone, Nicolás Abel
; Vera, Demián Augusto
; Iriarte, Daniela Ines
; Pomarico, Juan Antonio
; Macdonald, R.; Grosenick, D.
Fecha de publicación:
11/2020
Editorial:
IOP Publishing
Revista:
Biomedical Physics and Engineering Express
ISSN:
2057-1976
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
We present a novel method for obtaining a 3D absorption map of a tissue-like turbid slab in the near-infrared spectral range by tomosynthesis. Transmittance data are obtained for a large number of oblique projection directions by scanning a cw laser source across the surface of the slab and by using a CCD camera for spatially resolved light detection. A perturbation model of light transport is used to convert the intensity maps for the different projections into absorption maps. By applying the tomosynthesis approach to these new maps, 3D absorption information on embedded inclusions has been obtained for the first time. The number and the positions of the lateral offset detectors have been optimized by employing a structural similarity index for comparison of the reconstructed with the true absorption data. We present 3D reconstruction of absorption maps using both Monte Carlo simulations and experiments on phantoms with breast-like optical properties. A comparison with conventional 3D reconstruction by a finite element approach shows the superior location performance of tomosynthesis.
Palabras clave:
CW
,
MULTIPLE SCATTERING
,
NIR
,
TISSUE OPTICS
,
TOMOSYNTHESIS
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Articulos(CIFICEN)
Articulos de CENTRO DE INV. EN FISICA E INGENIERIA DEL CENTRO DE LA PCIA. DE BS. AS.
Articulos de CENTRO DE INV. EN FISICA E INGENIERIA DEL CENTRO DE LA PCIA. DE BS. AS.
Citación
Carbone, Nicolás Abel; Vera, Demián Augusto; Iriarte, Daniela Ines; Pomarico, Juan Antonio; Macdonald, R.; et al.; Camera-based CW diffuse optical tomography for obtaining 3D absorption maps by means of digital tomosynthesis; IOP Publishing; Biomedical Physics and Engineering Express; 6; 6; 11-2020; 1-18
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