Artículo
Naturally monozygotic quadruplets in a Braford cow confirmed by DNA analysis: A case report
Rogberg Muñoz, Andres
; Castillo, Nadia Sabiela
; Zappa, María Eugenia
; Crespi, Julian Alejandro
; Villegas Castagnasso, Egle Etel
; Gomez, Paula Macarena
; Peral Garcia, Pilar
; Giovambattista, Guillermo
Fecha de publicación:
09/2020
Editorial:
Wiley Blackwell Publishing, Inc
Revista:
Reproduction in Domestic Animals
ISSN:
0936-6768
e-ISSN:
1439-0531
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Cattle are a monotocous species, despite naturally conceived multiple births are sometimes observed. Although the number of twins has consistently increased, triplet and quadruplet pregnancies represent 0.015% and 0.004% of the total births, respectively. Multiple births are the result of multiple ovulation and/or the spontaneous cleavage of one fertilized oocyte, which is known as monozygotic (MZ) twinning. In cattle, approximately 5% to 14% of all twin births are MZ, and births with more than two MZ calves are extremely rare. Monozygotic animals are genetically identical, and those derived from two or more zygotes are genetically different. Furthermore, the presence of placental vascular anastomosis can result in foetal chimerism. Notwithstanding, animals born as single calves can be chimeras when one of the foetal twins dies undetected in utero. Here, we used DNA testing to study the zygotic condition of an unusual female quadruplet born from a Braford cow bred in a multi-sire natural mating system without hormone stimulation. Two tissues with different embryological origin were sampled to test zygosity and possible chimerism. The results showed an identical genotype, confirming they all originated in an MZ pregnancy and suggesting the lack of chimerism in all animals. The use of MZ twins in breeding and selection systems provides an alternative to the conventional progeny testing. Some works have suggested a genetic background of MZ twins in humans. This female and her daughters could be the founders of a lineage to study the possible inheritance of MZ multiple births in cattle.
Palabras clave:
CATTLE
,
DNA
,
MONOZYGOTIC
,
QUADRUPLET
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Articulos(IGEVET)
Articulos de INST.DE GENETICA VET ING FERNANDO NOEL DULOUT
Articulos de INST.DE GENETICA VET ING FERNANDO NOEL DULOUT
Citación
Rogberg Muñoz, Andres; Castillo, Nadia Sabiela; Zappa, María Eugenia; Crespi, Julian Alejandro; Villegas Castagnasso, Egle Etel; et al.; Naturally monozygotic quadruplets in a Braford cow confirmed by DNA analysis: A case report; Wiley Blackwell Publishing, Inc; Reproduction in Domestic Animals; 55; 9; 9-2020; 1267-1270
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