Artículo
The lncRNA APOLO interacts with the transcription factor WRKY42 to trigger root hair cell expansion in response to cold
Moison, Michael
; Martinez Pacheco, Javier
; Lucero, Leandro Exequiel
; Fonouni-farde, Camille Audrey
; Rodriguez Melo, Johan Stiben
; Mansilla, Natanael
; Christ, Aurélie; Bazin, Jérémie; Benhamed, Moussa; Ibañez, Fernando Julio
; Crespi, Martin; Estevez, Jose Manuel
; Ariel, Federico Damian
Fecha de publicación:
06/2021
Editorial:
Elsevier
Revista:
Molecular Plant
ISSN:
1674-2052
e-ISSN:
1752-9867
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Plant long noncoding RNAs (lncRNAs) have emerged as important regulators of chromatin dynamics, impacting on transcriptional programs leading to different developmental outputs. The lncRNA AUXIN-REGULATED PROMOTER LOOP (APOLO) directly recognizes multiple independent loci across the Arabidopsis genome and modulates their three-dimensional chromatin conformation, leading to transcriptional shifts. Here, we show that APOLO recognizes the locus encoding the root hair (RH) master regulator ROOT HAIR DEFECTIVE 6 (RHD6) and controls RHD6 transcriptional activity, leading to cold-enhanced RH elongation through the consequent activation of the transcription factor gene RHD6-like RSL4. Furthermore, we demonstrate that APOLO interacts with the transcription factor WRKY42 and modulates its binding to the RHD6 promoter. WRKY42 is required for the activation of RHD6 by low temperatures and WRKY42 deregulation impairs cold-induced RH expansion. Collectively, our results indicate that a novel ribonucleoprotein complex with APOLO and WRKY42 forms a regulatory hub to activate RHD6 by shaping its epigenetic environment and integrate signals governing RH growth and development.
Palabras clave:
APOLO
,
COLD TEMPERATURE
,
LONG NONCODING RNAS
,
RHD6
,
ROOT HAIRS
,
WRKY42
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Colecciones
Articulos (INIAB)
Articulos de INSTITUTO DE INVESTIGACIONES AGROBIOTECNOLOGICAS
Articulos de INSTITUTO DE INVESTIGACIONES AGROBIOTECNOLOGICAS
Articulos(IAL)
Articulos de INSTITUTO DE AGROBIOTECNOLOGIA DEL LITORAL
Articulos de INSTITUTO DE AGROBIOTECNOLOGIA DEL LITORAL
Articulos(IIBBA)
Articulos de INST.DE INVEST.BIOQUIMICAS DE BS.AS(I)
Articulos de INST.DE INVEST.BIOQUIMICAS DE BS.AS(I)
Citación
Moison, Michael; Martinez Pacheco, Javier; Lucero, Leandro Exequiel; Fonouni-farde, Camille Audrey; Rodriguez Melo, Johan Stiben; et al.; The lncRNA APOLO interacts with the transcription factor WRKY42 to trigger root hair cell expansion in response to cold; Elsevier; Molecular Plant; 14; 6; 6-2021; 937-948
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