Artículo
First detection and genetic characterization of porcine circovirus type 3 (PCV3) in Argentina and its association with reproductive failure
Serena, Maria Soledad
; Cappuccio, Javier Alejandro
; Barrales, Hernán; Metz, German Ernesto
; Aspitia, Carolina Gabriela; Lozada, María Inés
; Perfumo, Carlos Juan; Quiroga, María Alejandra; Piñeyro Piñeiro, Pablo Enrique
; Echeverria, Maria Gabriela
Fecha de publicación:
07/2021
Editorial:
Wiley Blackwell Publishing, Inc
Revista:
Transboundary And Emerging Diseases
ISSN:
1865-1674
e-ISSN:
1865-1682
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Porcine circovirus type 3 (PCV3) is considered a new circovirus and since it first description has been widely reported in most of the swine-producing countries. Multisystemic inflammation and reproductive failure are consistent and concerning issues associated with PCV3 infection. This report describes the clinical and pathological features of a chronic reproductive disorder in a swine herd in Argentina associated with the presence of PCV3. Mummified (n = 42) and stillborn piglets (n = 20) from a case of chronic reproductive disorder (Study A) and mummified and stillborn piglets (n = 141) from normal deliveries (Study B) were retrospectively assessed for the presence of multiple reproductive pathogens (PCV3, PCV2, ADV, PPV, Leptospira spp. and Brucella spp). On study, A PCV3 and PPV were detected in 15 and 8 pools, respectively, with a coinfection rate of 100% in all PPV-positive cases. Three out of 131 foetuses from three different sows from Study B were positive only for PCV3. Histological evaluation of hearts from stillborn also showed lesions similar to those previously described in the literature for PCV3-reproductive disease. Partial genome of PCV3 was amplified and phylogenetic analysis showed that strains of Study A and B clustered within the PCV3a and PCV3b clades, respectively. This study demonstrates, for the first time, the PCV3 has been circulating in Argentina at least since 2016 and its potential role in reproductive disorders. Further studies are warranted to determine the role of PCV3 in the reproductive disease complex and its prevalence in the swine industry in Argentina.
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Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Citación
Serena, Maria Soledad; Cappuccio, Javier Alejandro; Barrales, Hernán; Metz, German Ernesto; Aspitia, Carolina Gabriela; et al.; First detection and genetic characterization of porcine circovirus type 3 (PCV3) in Argentina and its association with reproductive failure; Wiley Blackwell Publishing, Inc; Transboundary And Emerging Diseases; 68; 4; 7-2021; 1761-1766
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