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dc.contributor.author
Rozés Salvador, María Victoria
dc.contributor.author
González Billault, Christian
dc.contributor.author
Conde, Cecilia Beatriz
dc.date.available
2021-09-13T18:32:31Z
dc.date.issued
2020-12
dc.identifier.citation
Rozés Salvador, María Victoria; González Billault, Christian; Conde, Cecilia Beatriz; The Recycling Endosome in Nerve Cell Development: One Rab to Rule Them All?; Frontiers Media S.A.; Frontiers in Cell and Developmental Biology; 8; 12-2020; 1-10
dc.identifier.issn
2296-634X
dc.identifier.uri
http://hdl.handle.net/11336/140244
dc.description.abstract
Endocytic recycling is an intracellular process that returns internalized molecules back to the plasma membrane and plays crucial roles not only in the reuse of receptor molecules but also in the remodeling of the different components of this membrane. This process is required for a diversity of cellular events, including neuronal morphology acquisition and functional regulation, among others. The recycling endosome (RE) is a key vesicular component involved in endocytic recycling. Recycling back to the cell surface may occur with the participation of several different Rab proteins, which are master regulators of membrane/protein trafficking in nerve cells. The RE consists of a network of interconnected and functionally distinct tubular subdomains that originate from sorting endosomes and transport their cargoes along microtubule tracks, by fast or slow recycling pathways. Different populations of REs, particularly those formed by Rab11, Rab35, and Arf6, are associated with a myriad of signaling proteins. In this review, we discuss the cumulative evidence suggesting the existence of heterogeneous domains of REs, controlling different aspects of neurogenesis, with a particular focus on the commonalities and singularities of these REs and their contribution to nerve development and differentiation in several animal models.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Frontiers Media S.A.
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
ARF6
dc.subject
DEVELOPMENT
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ENDOSOMAL PATHWAY
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NEURONAL DEVELOPMENT
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RAB11
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RAB35
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RABS
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RECYCLING ENDOSOME
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Bioquímica y Biología Molecular
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
The Recycling Endosome in Nerve Cell Development: One Rab to Rule Them All?
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-08-25T19:26:13Z
dc.journal.volume
8
dc.journal.pagination
1-10
dc.journal.pais
Suecia
dc.description.fil
Fil: Rozés Salvador, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad Nacional de Villa María; Argentina
dc.description.fil
Fil: González Billault, Christian. Universidad de Chile; Chile
dc.description.fil
Fil: Conde, Cecilia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
dc.journal.title
Frontiers in Cell and Developmental Biology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fcell.2020.603794/full
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fcell.2020.603794
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