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dc.contributor.author
Rocha, Luisa
dc.contributor.author
Lizette Frías Soria , Christian
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Ortiz, José G.
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Auzmendi, Jerónimo Andrés
dc.contributor.author
Lazarowski, Alberto
dc.date.available
2021-09-13T12:48:00Z
dc.date.issued
2020-01
dc.identifier.citation
Rocha, Luisa; Lizette Frías Soria , Christian; Ortiz, José G.; Auzmendi, Jerónimo Andrés; Lazarowski, Alberto; Is cannabidiol a drug acting on unconventional targets to control drug-resistant epilepsy; Wiley Blackwell Publishing, Inc; Epilepsia Open; 5; 1; 1-2020; 36-49
dc.identifier.issn
2470-9239
dc.identifier.uri
http://hdl.handle.net/11336/140176
dc.description.abstract
Cannabis has been considered as a therapeutic strategy to control intractable epilepsy. Several cannabis components, especially cannabidiol (CBD), induce antiseizure effects. However, additional information is necessary to identify the types of epilepsies that can be controlled by these components and the mechanisms involved in these effects. This review presents a summary of the discussion carried out during the 2nd Latin American Workshop on Neurobiology of Epilepsy entitled “Cannabinoid and epilepsy: myths and realities.” This event was carried out during the 10th Latin American Epilepsy Congress in San José de Costa Rica (September 28, 2018). The review focuses to discuss the use of CBD as a new therapeutic strategy to control drug-resistant epilepsy. It also indicates the necessity to consider the evaluation of unconventional targets such as P-glycoprotein, to explain the effects of CBD in drug-resistant epilepsy.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
CANNABIDIOL
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CANNABIS
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DRUG-RESISTANT EPILEPSY
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P-GLYCOPROTEIN
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Bioquímica y Biología Molecular
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
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Bioquímica y Biología Molecular
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
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Neurociencias
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Is cannabidiol a drug acting on unconventional targets to control drug-resistant epilepsy
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-09-07T18:49:27Z
dc.identifier.eissn
2470-9239
dc.journal.volume
5
dc.journal.number
1
dc.journal.pagination
36-49
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Hoboken, New Jersey
dc.description.fil
Fil: Rocha, Luisa. CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS ; INSTITUTO POLITÉCNICO NACIONAL;
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Fil: Lizette Frías Soria , Christian. CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS ; INSTITUTO POLITÉCNICO NACIONAL;
dc.description.fil
Fil: Ortiz, José G.. Universidad de Puerto Rico; Puerto Rico
dc.description.fil
Fil: Auzmendi, Jerónimo Andrés. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Fisiopatología y Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
dc.description.fil
Fil: Lazarowski, Alberto. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Fisiopatología y Bioquímica Clínica; Argentina
dc.journal.title
Epilepsia Open
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/epi4.12376
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/epi4.12376
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