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dc.contributor.author
Rosenstein, Ruth Estela
dc.contributor.author
Fernandez, Diego Carlos
dc.date.available
2017-03-16T21:53:44Z
dc.date.issued
2014-09
dc.identifier.citation
Rosenstein, Ruth Estela; Fernandez, Diego Carlos; Induction of ischemic tolerance as a promising treatment against diabetic retinopathy; Medknow Publications; Neural Regeneration Research; 9; 17; 9-2014; 1581-1584
dc.identifier.issn
1673-5374
dc.identifier.uri
http://hdl.handle.net/11336/14008
dc.description.abstract
Diabetic retinopathy is a leading cause of acquired blindness, and it is the most common ischemic disorder of the retina. Available treatments are not very effective. Efforts to inhibit diabetic retinopathy have focused either on highly specific therapeutic approaches for pharmacologic targets or using genetic approaches to change expression of certain enzymes. However, it might be wise to choose innovative treatment modalities that act by multiple potential mechanisms. The resistance to ischemic injury, or ischemic tolerance, can be transiently induced by prior exposure to a non-injurious preconditioning stimulus. A complete functional and histologic protection against retinal ischemic damage can be achieved by previous preconditioning with non-damaging ischemia. In this review, we will discuss evidence that supports that ischemic conditioning could help avert the dreaded consequences that results from retinal diabetic damage.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Medknow Publications
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Diabetic Retinopathy
dc.subject
Ischemic Tolerance
dc.subject
Retina
dc.subject
Ischemic Injury
dc.subject
Ischemic Conditioning
dc.subject.classification
Neurociencias
dc.subject.classification
Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Induction of ischemic tolerance as a promising treatment against diabetic retinopathy
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-03-06T17:07:12Z
dc.identifier.eissn
1876-7958
dc.journal.volume
9
dc.journal.number
17
dc.journal.pagination
1581-1584
dc.journal.pais
India
dc.journal.ciudad
Bombay
dc.description.fil
Fil: Rosenstein, Ruth Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Laboratorio de Neuroquímica Retiniana y Oftalmología Experimental; Argentina
dc.description.fil
Fil: Fernandez, Diego Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Laboratorio de Neuroquímica Retiniana y Oftalmología Experimental; Argentina
dc.journal.title
Neural Regeneration Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.nrronline.org/article.asp?issn=1673-5374;year=2014;volume=9;issue=17;spage=1581;epage=1584;aulast=Rosenstein
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.4103/1673-5374.141782


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