Mostrar el registro sencillo del ítem
dc.contributor.author
Lehotay, Steven J.
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.contributor.author
de Zeeuw, Jaap
dc.contributor.author
Sapozhnikova, Yelena
dc.contributor.author
Michlig, Nicolás
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.contributor.author
Rousova Hepner, Jana
dc.contributor.author
Konschnik, Joseph
dc.date.available
2021-09-02T02:05:36Z
dc.date.issued
2020-08
dc.identifier.citation
Lehotay, Steven J.; de Zeeuw, Jaap; Sapozhnikova, Yelena; Michlig, Nicolás; Rousova Hepner, Jana; et al.; There is no Time to waste: low-pressure gas chromatography-mass spectrometry is a proven solution for fast, sensitive, and robust GC-MS analysis; Advanstar Communications Inc.; LCGC North America; 38; 8; 8-2020; 1-10
dc.identifier.issn
1527-5949
dc.identifier.uri
http://hdl.handle.net/11336/139507
dc.description.abstract
Low-pressure gas chromatography (LPGC) has been known to be advantageous compared to standard GC since Giddings first described the concept in 1962, but a practical solution for its use eluded analytical chemists until the year 2000, when de Zeeuw fashioned a simple guard column restrictor concept to maintain positive inlet pressure for a wide-bore analytical column under vacuum. Initially introduced as rapid mass spectrometry (MS), de Zeeuw’s invention made LPGC practical in nearly any GC application using MS for detection. Lehotay and associates have demonstrated the advantageous features, excellent performance, and practical utility of LPGC–MS in dozens of publications since 2001. In our experience, LPGC–MS is the most practical and beneficial fast-GC technique available to achieve <10 min analyses in applications that typically take 20–40 min. Sample capacity and column robustness are increased greatly using LPGC to permit large-volume injection with standard inlets without column maintenance, and, because vacuum conditions generate taller and narrower peaks that are still suitable for standard MS data acquisition rates, sensitivity is also increased. Furthermore, enhanced selectivity of detection using modern MS tools and software compensate for reduced chromatographic peak capacity. In our view, LPGC–MS should be the first option for evaluation in many GC–MS applications to provide fast, sensitive, and robust analyses.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Advanstar Communications Inc.
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
LOW PRESSURE GAS CHROMATOGRAPHY
dc.subject
FAST CHROMATOGRAPHY
dc.subject.classification
Química Analítica
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
Ciencias Químicas
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.title
There is no Time to waste: low-pressure gas chromatography-mass spectrometry is a proven solution for fast, sensitive, and robust GC-MS analysis
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-03-15T14:32:45Z
dc.journal.volume
38
dc.journal.number
8
dc.journal.pagination
1-10
dc.journal.pais
Estados Unidos
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.description.fil
Fil: Lehotay, Steven J.. Eastern Regional Research Center; Estados Unidos
dc.description.fil
Fil: de Zeeuw, Jaap. Restek Corporation; Estados Unidos
dc.description.fil
Fil: Sapozhnikova, Yelena. Eastern Regional Research Center; Estados Unidos
dc.description.fil
Fil: Michlig, Nicolás. Eastern Regional Research Center; Estados Unidos. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Rousova Hepner, Jana. Restek Corporation; Estados Unidos
dc.description.fil
Fil: Konschnik, Joseph. Restek Corporation; Estados Unidos
dc.journal.title
LCGC North America
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.chromatographyonline.com/view/vol-38-no-8-lcgc-north-america-august-2020-regular-issue-pdf
Archivos asociados