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dc.contributor.author
Enriz, Ricardo Daniel
dc.contributor.author
Freile, Monica Liliana
dc.date.available
2021-08-23T15:34:24Z
dc.date.issued
2006-06
dc.identifier.citation
Enriz, Ricardo Daniel; Freile, Monica Liliana; Structure-activity relationship of berberine and derivatives acting as antifungal compounds; Asociación Química Argentina; Journal of the Argentine Chemical Society; 94; 1-3; 6-2006; 113-119
dc.identifier.issn
0365-0375
dc.identifier.uri
http://hdl.handle.net/11336/138703
dc.description.abstract
A structure-activity relationship study of berberine and structurally related compounds is reported. Berberine, was chemically modified in order to obtain canadine and oxyberberine. The in vitro evaluation of antifungal activity of berberine, canadine, oxyberberine, liriodenine, o-methyl-mostachatoline and other four derivatives is also reported here. Our results allow us to determine the minimal structural requirements to produce the antifungal response and can provide a guide for the design of new compounds with these properties.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Asociación Química Argentina
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Berberine
dc.subject
Antifungal activity
dc.subject
Structural requirements
dc.subject.classification
Otras Ciencias Químicas
dc.subject.classification
Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Structure-activity relationship of berberine and derivatives acting as antifungal compounds
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-07-29T13:54:55Z
dc.journal.volume
94
dc.journal.number
1-3
dc.journal.pagination
113-119
dc.journal.pais
Argentina
dc.journal.ciudad
Buenos Aires
dc.description.fil
Fil: Enriz, Ricardo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina
dc.description.fil
Fil: Freile, Monica Liliana. Universidad Nacional de la Patagonia "San Juan Bosco"; Argentina
dc.journal.title
Journal of the Argentine Chemical Society
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.aqa.org.ar/index.php/volumenes-publicados/47-vol-94-1-3-january-june-2006
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