Artículo
Antibiofilm effect of mesoporous titania coatings on Pseudomonas aeruginosa biofilms
Pezzoni, Magdalena
; Catalano, Paolo Nicolás
; Delgado, Diana C.; Pizarro, Ramón Augusto; Bellino, Martin Gonzalo
; Costa, Cristina Susana
Fecha de publicación:
01/2020
Editorial:
Elsevier Science SA
Revista:
Journal of Photochemistry and Photobiology B: Biology
ISSN:
1011-1344
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Activation of photocatalytic titania by ultraviolet-A (UVA) radiation has been proposed as a good approach for combating bacteria. Titania powder, in solution or immobilized on a surface, has excellent UVA-assisted killing properties on several microorganisms. However, these properties could not be demonstrated in biofilms of Pseudomonas aeruginosa, a resistant opportunistic human pathogen that can cause severe complications in patients who are immunocompromised or have burn wounds or cystic fibrosis. P. aeruginosa biofilms have detrimental effects on health and industry, causing serious economic damage. In this study, the effect of titania photocatalysis for controlling P. aeruginosa biofilms was investigated by employing different coatings obtained through sol-gel and evaporation-induced self-assembly. Biofilms were grown on non-mesoporous and mesoporous titania surfaces with different pore sizes, which were achieved based on the use of surfactants Brij-58 and Pluronics-F127. In addition, two structural forms of titania were assayed: amorphous and anatase. As well as inhibiting biofilm formation, these coatings significantly enhanced the bactericidal effect of UVA on P. aeruginosa biofilms. The most efficient surface with regard to total antibacterial effect was the mesoporous Brij-58-templated anatase film, which, compared to control biofilms, decreased the number of viable bacteria by about 5 orders, demonstrating the efficacy of this methodology as a disinfection system.
Palabras clave:
ANTIBIOFILM COATING
,
BIOFILM
,
MESOPOROUS
,
PHOTOCATALYSIS
,
PSEUDOMONAS
,
TITANIA
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos (UE-INN - NODO CONSTITUYENTES)
Articulos de UNIDAD EJECUTORA INSTITUTO DE NANOCIENCIA Y NANOTECNOLOGIA - NODO CONSTITUYENTES
Articulos de UNIDAD EJECUTORA INSTITUTO DE NANOCIENCIA Y NANOTECNOLOGIA - NODO CONSTITUYENTES
Articulos(CCT - PATAGONIA NORTE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - PATAGONIA NORTE
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - PATAGONIA NORTE
Citación
Pezzoni, Magdalena; Catalano, Paolo Nicolás; Delgado, Diana C.; Pizarro, Ramón Augusto; Bellino, Martin Gonzalo; et al.; Antibiofilm effect of mesoporous titania coatings on Pseudomonas aeruginosa biofilms; Elsevier Science SA; Journal of Photochemistry and Photobiology B: Biology; 203; 111762; 1-2020; 1-7
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