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dc.contributor.author
Corach, Daniel  
dc.contributor.author
Vullo, C.  
dc.contributor.author
Sala, A.  
dc.contributor.author
Catelli, M.  
dc.contributor.author
Caputo, M.  
dc.contributor.author
Romero, M.  
dc.contributor.author
Ginart, Santiago  
dc.contributor.author
Garrigós, L.  
dc.contributor.author
Fonderbrider, L.  
dc.contributor.author
Somigliana, C.  
dc.date.available
2021-07-23T18:22:15Z  
dc.date.issued
2019-12  
dc.identifier.citation
Corach, Daniel; Vullo, C.; Sala, A.; Catelli, M.; Caputo, M.; et al.; Re-evaluation of DNA based identification results of victims of a terrorist attack 25 years later; Elsevier; Forensic Science International: Genetics Supplement Series; 7; 1; 12-2019; 735-736  
dc.identifier.issn
1875-1768  
dc.identifier.uri
http://hdl.handle.net/11336/136795  
dc.description.abstract
In July 1994 there was a second terrorist attack against a Jewish institution in Buenos Aires city. It targeted the Argentine Israelite Mutual Association (AMIA) and the bomb toppled its building, killed 85 and hurt over 300 people. The Supreme Court ordered DFPS/SHDG to carry out the identification of the fragmented remains by means of DNA analysis. At that time five VNTRs, seven STRs including five autosomal, one X, and one on the Y chromosome, mtDNA sequencing (HVR I and II) and MVR were used. The techniques used were all manual, southern blot and polyacrylamide gels with radioactive probes or primer detection. The first report was presented on November 7, 1994. In addition to the molecular data, identifications were made using conventional forensic criteria: dactyloscopy, radiography, dentistry and personal traits. In July 2016, the AMIA Investigative Investigation Unit wanted to clarify the identity of additional victims and asked the DFPS/SHDG and as a second opinion laboratory the Argentine team of Forensic Anthropology (EAAF), to analyze samples in parallel, compare them to the results reported in 1994, and perform additional tests on samples not previously analyzed by DNA typing. Both laboratories used automated platforms (ABI 3500); commercial kits Powerplex Fusion, Identifiler and mtDNA sequencing. Although TH01 and vWA are the only tested STR markers in 1994 that are still in use, most results reported in 1994 were confirmed by both laboratories. Additionally, it was possible to identify a victim whose material had initially been analyzed but, given its state of degradation, it had not been possible to obtain a genetic profile. The use of more sensitive megaplexes made it possible to identify a missing person 23 years later. The overall results demonstrate the robustness of the DNA analyses and the great increase in the sensitivity of the new analytical systems used and underscore the importance of including a second opinion lab to warrant the quality of the results.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
DNA TYPING EVOLUTION  
dc.subject
DVI  
dc.subject
SECOND OPINION  
dc.subject.classification
Genética y Herencia  
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Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Re-evaluation of DNA based identification results of victims of a terrorist attack 25 years later  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2021-04-28T21:36:42Z  
dc.identifier.eissn
1875-175X  
dc.journal.volume
7  
dc.journal.number
1  
dc.journal.pagination
735-736  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina  
dc.description.fil
Fil: Vullo, C.. No especifíca;  
dc.description.fil
Fil: Sala, A.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina  
dc.description.fil
Fil: Catelli, M.. No especifíca;  
dc.description.fil
Fil: Caputo, M.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina  
dc.description.fil
Fil: Romero, M.. No especifíca;  
dc.description.fil
Fil: Ginart, Santiago. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina  
dc.description.fil
Fil: Garrigós, L.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina  
dc.description.fil
Fil: Fonderbrider, L.. No especifíca;  
dc.description.fil
Fil: Somigliana, C.. No especifíca;  
dc.journal.title
Forensic Science International: Genetics Supplement Series  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S1875176819300216  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.fsigss.2019.10.156