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dc.contributor.author
Vissio, Claudina
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dc.contributor.author
Mella, Armin
dc.contributor.author
Amestica, Luis
dc.contributor.author
Pol, Martin
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dc.date.available
2021-07-15T20:10:44Z
dc.date.issued
2020-02
dc.identifier.citation
Vissio, Claudina; Mella, Armin; Amestica, Luis; Pol, Martin; Noninferiority study evaluating the efficacy of a teat disinfectant containing copper and zinc for prevention of naturally occurring intramammary infections in an automatic milking system; American Dairy Science Association; Journal of Dairy Science; 103; 2; 2-2020; 1776-1784
dc.identifier.issn
0022-0302
dc.identifier.uri
http://hdl.handle.net/11336/136284
dc.description.abstract
The aim of this study was to demonstrate the noninferiority of a novel teat disinfectant based on copper and zinc (ZkinCu; Copper Andino, Santiago de Chile, Chile) compared with a previously proven glycolic acid active disinfectant (OceanBlu; DeLaval, Kansas City, MO) as a positive control, with respect to the incidence of new intramammary infections under natural challenge conditions on a commercial robotic dairy farm. This study was conducted in 6 robotic pens of approximately 60 milking cows each. The pens were randomly assigned to 1 of the 2 studied disinfectants. Throughout the 8 wk study, the same pre- and post-milking teat disinfectant was used in each pen. The same milking procedures were used in each robot throughout the study. Pre-milking hygiene consisted of applying the disinfectant (OceanBlu or ZkinCu) with the robotic arm. The same product was applied on the teats after milking. At the beginning of the study, all quarters of all study cows were sampled. In successive samplings (wk 2, 4, 6, and 8), composite milk samples were collected on farm to determine SCC. Once composite SCC results were available (2 d) and based on an SCC of ≥100,000 cells/mL, quarter milk samples underwent bacteriological culture. Clinical mastitis was identified by study personnel. Intramammary infection in biweekly quarter milk samples was determined based on composite SCC levels (≥100,000 cells/mL) and the presence of bacteria. A new IMI was defined as a quarter in which the organism isolated was not present in the previous bacteriological sample, or the previous composite SCC sample was <100,000 cells/mL. Clinical mastitis samples were also considered to be new IMI. The trial was designed as a positive control field trial, in which the objective was to show noninferiority of ZkinCu versus the control (OceanBlu). The overall crude incidences of new IMI for 2 wk at risk were 4.9 and 7.3% for the ZkinCu and OceanBlu groups, respectively. The predominant organisms recovered from quarters with new IMI were Streptococcus uberis, Corynebacterium spp., and coagulase-negative staphylococci in both the ZkinCu and OceanBlu groups. The risk of infection in the OceanBlu group was higher (β = 0.644; 95% confidence interval = 0.05–1.22). The interaction of treatment by week was not significant. The new IMI rate estimates (95% confidence interval) for ZkinCu and OceanBlu were 1.7% (0.8–2.5) and 3.2% (1.7–4.7), respectively. One novel aspect of this study is that it was one of the first commercial noninferiority trials to evaluate a new pre- and post-milking teat disinfectant in a dairy herd with an automatic milking system. The experimental teat disinfectant ZkinCu, evaluated in this field trial with naturally occurring IMI, showed noninferiority relative to the positive control for the prevention of new IMI. This study was conducted in a herd with an automatic milking system, and the results are applicable to herds with similar characteristics. Additional studies are needed to ensure reproducibility under different management conditions.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
American Dairy Science Association
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
AUTOMATIC MILKING
dc.subject
INTRAMAMMARY INFECTION
dc.subject
NONINFERIORITY TRIAL
dc.subject
TEAT DISINFECTANT
dc.subject.classification
Ciencias Veterinarias
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dc.subject.classification
Ciencias Veterinarias
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dc.subject.classification
CIENCIAS AGRÍCOLAS
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dc.title
Noninferiority study evaluating the efficacy of a teat disinfectant containing copper and zinc for prevention of naturally occurring intramammary infections in an automatic milking system
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-04-23T16:41:39Z
dc.identifier.eissn
1525-3198
dc.journal.volume
103
dc.journal.number
2
dc.journal.pagination
1776-1784
dc.journal.pais
Estados Unidos
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dc.journal.ciudad
Champaign, Illinois
dc.description.fil
Fil: Vissio, Claudina. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina
dc.description.fil
Fil: Mella, Armin. Universidad Austral de Chile; Chile
dc.description.fil
Fil: Amestica, Luis. R&d Copper Andino Sa; Chile
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Fil: Pol, Martin. Lactodiagnóstico Sur SRL; Argentina
dc.journal.title
Journal of Dairy Science
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0022030219310951
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3168/jds.2018-16217
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