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dc.contributor.author
Besuhli, Valeria
dc.contributor.author
de Laurentiis, Andrea
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Les Dees, W.
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Endruhn, Axel
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Rettori, Valeria
dc.date.available
2017-03-07T20:16:04Z
dc.date.issued
2014-02
dc.identifier.citation
Besuhli, Valeria; de Laurentiis, Andrea; Les Dees, W.; Endruhn, Axel ; Rettori, Valeria; Host neuro-immuno-endocrine responses in Periodontal Disease; Bentham Science Publishers; Current Pharmaceutical Design.; 20; 29; 2-2014; 4749-4759
dc.identifier.issn
1381-6128
dc.identifier.uri
http://hdl.handle.net/11336/13607
dc.description.abstract
Periodontitis is a chronic inflammatory complex disease caused by microorganisms. It may be influenced by diverse systemic disorders, environmental, genetic and socio-psychological factors with the ability to alter the balance of the host neuro-immunoendocrine responses. It is characterized by the progressive destruction of the tooth supporting apparatus leading to tooth loss, with possible impact on general health. Starting with a brief description of the periodontium, etiopathogenesis, repair processes and several physiological mechanisms and their disarray on periodontium response to bacterial challenge. Following, the negative effects of stress on the disease and some remarks on the recently discovered effects of oxytocin that modulate stress response and its role in individual coping mechanisms to stress. We also focus on the participation of components and functions of endocannabinoid system with anti-inflammatory actions on gingiva. Finally, a discussion that may link between diabetes, cardiovascular diseases, stroke and metabolic syndrome associated with periodontal disease; all of them sharing a common denominator that is inflammation and oxidative stress.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Bentham Science Publishers
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Gingiva
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Neuropeptides
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Inflammation
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Stress
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Endocannabinoids
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Cytokines
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Otras Ciencias de la Salud
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Host neuro-immuno-endocrine responses in Periodontal Disease
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-03-06T15:25:43Z
dc.journal.volume
20
dc.journal.number
29
dc.journal.pagination
4749-4759
dc.journal.pais
Emiratos Árabes Unidos
dc.journal.ciudad
Sharjah
dc.description.fil
Fil: Besuhli, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Universidad Maimonides; Argentina
dc.description.fil
Fil: de Laurentiis, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina
dc.description.fil
Fil: Les Dees, W.. Texas AyM University; Estados Unidos
dc.description.fil
Fil: Endruhn, Axel. Universidad Maimonides; Argentina
dc.description.fil
Fil: Rettori, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos; Argentina
dc.journal.title
Current Pharmaceutical Design.
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/120069/article
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/1381612820666140130204043


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