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dc.contributor.author
Illanes, Andrés
dc.contributor.author
Guzmán, Fanny
dc.contributor.author
Barberis, Sonia Esther
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dc.contributor.other
Hughes, Andrew B.
dc.date.available
2021-07-12T14:14:59Z
dc.date.issued
2009
dc.identifier.citation
Illanes, Andrés; Guzmán, Fanny; Barberis, Sonia Esther; Proteases as powerful catalysts for organic synthesis; Wiley VCH Verlag; 2; 2009; 341-377
dc.identifier.isbn
978-3-527-32098-1
dc.identifier.uri
http://hdl.handle.net/11336/135847
dc.description.abstract
Enzymes are the catalysts of life. In fact, each biochemical reaction of cell metabolism requires catalysis by a specific enzyme to proceed at the pace required to sustain life. Enzymes are protein molecules that have evolved to perform efficiently under the mild conditions required to preserve the functionality and integrity of biological systems, and so can be considered as catalysts that have been optimized through evolution to perform their physiological task. Enzymes are capable of catalyzing a wide range of chemical reactions and it is not presumptuous to state that any organic chemical reaction already described might have an enzyme able to catalyze it. In fact, nature is an unlimited source of enzymes; to get the right enzyme for a certain chemical reaction is then a matter of searching, and this is certainly challenging and exciting if one realizes that only a very small fraction of all living forms have already been isolated. Moreover, it is now possible to obtain DNA metagenomic pools from the environment without requiring to know the organism from which it comes and then express it into a suitable host organism, and also to perform genetic remodeling of structural genes by site-directed mutagenesis.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley VCH Verlag
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
PROTEASES
dc.subject
ORGANIC SYNTHESIS
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MECHANISMS
dc.subject.classification
Bioprocesamiento Tecnológico, Biocatálisis, Fermentación
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dc.subject.classification
Biotecnología Industrial
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dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
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dc.title
Proteases as powerful catalysts for organic synthesis
dc.type
info:eu-repo/semantics/publishedVersion
dc.type
info:eu-repo/semantics/bookPart
dc.type
info:ar-repo/semantics/parte de libro
dc.date.updated
2020-08-05T16:56:56Z
dc.journal.volume
2
dc.journal.pagination
341-377
dc.journal.pais
Alemania
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dc.journal.ciudad
Weinheim
dc.description.fil
Fil: Illanes, Andrés. Pontificia Universidad Catolica de Valparaiso. Escuela de Ingeniería Bioquímica; Chile
dc.description.fil
Fil: Guzmán, Fanny. Pontificia Universidad Católica de Valparaíso; Chile
dc.description.fil
Fil: Barberis, Sonia Esther. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich". Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich"; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1002/9783527631780.ch8
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/9783527631780.ch8
dc.conicet.paginas
683
dc.source.titulo
Amino acids, peptides and proteins in organic chemistry: Modified amino acids, organocatalysis and enzymes
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