Artículo

Detection of plasmid-mediated colistin resistance by colistin pre-diffusion and inhibition with EDTA test (CPD-E) in Enterobactereaceae

Yauri Condor, Katherine; Gonzales Escalante, Edgar; Di Conza, José AlejandroIcon ; Gutkind, Gabriel OsvaldoIcon
Fecha de publicación: 12/2019
Editorial: Elsevier Science
Revista: Journal of Microbiological Methods
ISSN: 0167-7012
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

A phenotypic assay based on colistin pre-diffusion and differential inhibition of Mobile Colistin Resistance (MCR) protein activity by EDTA showed that, of the 92 strains tested, all MCR producers (49) exhibited an increase ≥5 mm in the inhibition zone around the area of pre-diffusion in the presence of EDTA, in comparison with colistin alone. Results suggest that CPD-E may differentiate MCR-producing microorganisms from resistant microorganisms without this marker.
Palabras clave: Colistina , mcr-1 , Detección fenotipica
 
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/135053
URL: https://www.sciencedirect.com/science/article/abs/pii/S0167701219307778
DOI: http://dx.doi.org/10.1016/j.mimet.2019.105759
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Citación
Yauri Condor, Katherine; Gonzales Escalante, Edgar; Di Conza, José Alejandro; Gutkind, Gabriel Osvaldo; Detection of plasmid-mediated colistin resistance by colistin pre-diffusion and inhibition with EDTA test (CPD-E) in Enterobactereaceae; Elsevier Science; Journal of Microbiological Methods; 167; 12-2019; 1-4
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