Mostrar el registro sencillo del ítem
dc.contributor.author
Zhu, Sirui
dc.contributor.author
Estevez, Jose Manuel
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.contributor.author
Liao, Hongdong
dc.contributor.author
Zhu, Yonghua
dc.contributor.author
Yang, Tao
dc.contributor.author
Li, Chiyu
dc.contributor.author
Wang, Yichuan
dc.contributor.author
Li, Lan
dc.contributor.author
Liu, Xuanming
dc.contributor.author
Martinez Pacheco, Javier
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.contributor.author
Guo, Hongwei
dc.contributor.author
Yu, Feng
dc.date.available
2021-06-10T15:46:08Z
dc.date.issued
2020-01
dc.identifier.citation
Zhu, Sirui; Estevez, Jose Manuel; Liao, Hongdong; Zhu, Yonghua; Yang, Tao; et al.; The RALF1–FERONIA Complex Phosphorylates eIF4E1 to Promote Protein Synthesis and Polar Root Hair Growth; Oxford University Press; Molecular Plant; 13; 5; 1-2020; 698-716
dc.identifier.issn
1674-2052
dc.identifier.uri
http://hdl.handle.net/11336/133618
dc.description.abstract
The molecular links between extracellular signals and the regulation of localized protein synthesis in plant cells are poorly understood. Here, we show that in Arabidopsis thaliana, the extracellular peptide RALF1 and its receptor, the FERONIA receptor kinase, promote root hair (RH) tip growth by modulating protein synthesis. We found that RALF1 promotes FERONIA-mediated phosphorylation of eIF4E1, a eukaryotic translation initiation factor that plays a crucial role in the control of mRNA translation rate. Phosphorylated eIF4E1 increases mRNA affinity and modulates mRNA translation and, thus, protein synthesis. The mRNAs targeted by the RALF1–FERONIA–eIF4E1 module include ROP2 and RSL4, which are important regulators of RH cell polarity and growth. RALF1 and FERONIA are expressed in a polar manner in RHs, which facilitate eIF4E1 polar localization and thus may control local ROP2 translation. Moreover, we demonstrated that high-level accumulation of RSL4 exerts negative-feedback regulation of RALF1 expression by directly binding the RALF1 gene promoter, determining the final RH size. Our study reveals that the link between RALF1–FERONIA signaling and protein synthesis constitutes a novel component regulating cell expansion in these polar growing cells.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Oxford University Press
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
EIF4E1
dc.subject
FER
dc.subject
POLAR CELL GROWTH
dc.subject
RALF1
dc.subject
ROOT HAIRS
dc.subject
RSL4
dc.subject.classification
Bioquímica y Biología Molecular
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
Ciencias Biológicas
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.title
The RALF1–FERONIA Complex Phosphorylates eIF4E1 to Promote Protein Synthesis and Polar Root Hair Growth
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-05-19T19:38:07Z
dc.identifier.eissn
1752-9867
dc.journal.volume
13
dc.journal.number
5
dc.journal.pagination
698-716
dc.journal.pais
Reino Unido
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.journal.ciudad
Oxford
dc.description.fil
Fil: Zhu, Sirui. Hunan University; China
dc.description.fil
Fil: Estevez, Jose Manuel. Universidad Andrés Bello; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
dc.description.fil
Fil: Liao, Hongdong. Hunan University; China
dc.description.fil
Fil: Zhu, Yonghua. Hunan University; China
dc.description.fil
Fil: Yang, Tao. Central South University of Forestry and Technology; China
dc.description.fil
Fil: Li, Chiyu. Hunan University; China
dc.description.fil
Fil: Wang, Yichuan. Southern University of Science and Technology; China
dc.description.fil
Fil: Li, Lan. Hunan University; China
dc.description.fil
Fil: Liu, Xuanming. Hunan University; China
dc.description.fil
Fil: Martinez Pacheco, Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
dc.description.fil
Fil: Guo, Hongwei. Southern University of Science and Technology; China
dc.description.fil
Fil: Yu, Feng. Hunan University; China
dc.journal.title
Molecular Plant
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.molp.2019.12.014
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.cell.com/molecular-plant/fulltext/S1674-2052(19)30431-9
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1674205219304319
Archivos asociados