Endocannabinoid signaling impairs syncytialization: Using flow cytometry to evaluate forskolin-induced cell fusion

Cytotrophoblast cells fuse to form the syncytiotrophoblast, the main structure responsible for the placenta's specialized functions. This complex process denominated syncytialization is fundamental for a correct pregnancy outcome. We observed that the endocannabinoid anandamide disrupts syncytialization employing traditional techniques and flow cytometry in BeWo cell line.

Palabras clave: ANANDAMIDE , BEWO , CANNABINOIDS , ENDOCANNABINOID , FLOW-CYTOMETRY , SYNCYTIALIZATION

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Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)

Identificadores

URI: http://hdl.handle.net/11336/132122

URL: https://linkinghub.elsevier.com/retrieve/pii/S0143400420304252

DOI: http://dx.doi.org/10.1016/j.placenta.2020.10.028

Colecciones

Articulos(CEFYBO)
Articulos de CENTRO DE ESTUDIOS FARMACOLOGICOS Y BOTANICOS

Articulos(IFIBIO HOUSSAY)
Articulos de INSTITUTO DE FISIOLOGIA Y BIOFISICA BERNARDO HOUSSAY

Citación

Etcheverry, Tomás; Accialini, Paula Lucia; Palligas, Marcos Abdul; Loureiro, Florencia; Saraco, Nora Isabel; et al.; Endocannabinoid signaling impairs syncytialization: Using flow cytometry to evaluate forskolin-induced cell fusion; W B Saunders Co Ltd; Placenta; 103; 1-2021; 152-155

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