Evento

Snake venomics of Crotalus durissus terrificus from Argentina

Fusco, Luciano SebastianIcon ; Neto, Emídio; Francisco, Aleff; Alfonso, Jorge; Siqueira, Claudia; Leiva, Laura Cristina Ana; Pimenta, Daniel; Soares, Andreimar
Tipo del evento: Congreso
Nombre del evento: 20th World Congress of the International Society on Toxinology
Fecha del evento: 08/09/2019
Institución Organizadora: International Society of Toxinology;
Título de la revista: Toxicon
Editorial: Elsevier
ISSN: 0041-0101
Idioma: Inglés
Clasificación temática:

Resumen

Envenomation by C.d.terrificus is a relevant public health problem in South America. To date, there are no proteomic studies of C. d.terrificus venom from Argentina, so we here report the venom composition from specimens that inhabit the Northeast Argentina region. The proteins were separated by reverse-phase HPLC and identified by mass spectrometry. C. d.terrifius proteome showed the presence of 10-15 main toxins belonging to the following protein families: disintegrins, PLA2s, serine proteinases, vascular endothelial growth factor-like (VEGF), L-amino acid oxidases, C-type lectins-like and phosphodiesterases. The neurotoxic proteins, crotoxin and crotamine, represent the 74.8 % of proteins of the C.d.terrificus venome.....
Palabras clave: snake venom , rattlesnake , proteomic
 
Archivos asociados
Tamaño: 45.35Kb
Formato: PDF
.
Licencia
info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/130120
URL: https://www.sciencedirect.com/science/article/abs/pii/S0041010119308724
Colecciones
Eventos(IQUIBA-NEA)
Eventos de INSTITUTO DE QUIMICA BASICA Y APLICADA DEL NORDESTE ARGENTINO
Citación
Snake venomics of Crotalus durissus terrificus from Argentina; 20th World Congress of the International Society on Toxinology; Buenos Aires; Argentina; 2019
Compartir