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Artículo

Effect of anodized zirconium implants on early osseointegration process in adult rats: a histological and histomorphometric study

Tano de la Hoz, María FlorenciaIcon ; Katunar, Maria RosaIcon ; Gonzalez, Ariel; Gomez Sanchez, Andrea ValeriaIcon ; Díaz, Alcira Ofelia; Ceré, SilviaIcon
Fecha de publicación: 22/11/2019
Editorial: Springer
Revista: Progress in Biomaterial
ISSN: 2194-0509
e-ISSN: 2194-0517
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:
Recubrimientos y Películas

Resumen

Since surface plays a key role in bioactivity, the response of the host to the biomaterial will determine the success or failure of the prosthesis. The purpose of this study is to make an exhaustive analysis of the histological and histochemical characteristics of new bone tissue around Zr implants anodized at 60 V (Zr60) supported by histomorphometric methods in a rat model. Fibrous tissue was observed around the control implants (Zr0) and osteoblasts were identifed on the trabeculae close to the implantation site that showed typical cytological characteristics of active secretory cells, regardless of the surface condition. The histomorphometrical analysis revealed a signifcant increase in cancellous bone volume, trabecular thickness and in trabecular number together with a decrease in trabecular separation facing Zr60. TRAP staining showed that there was a relative increase in the number of osteoclasts for Zr60. In addition, a larger number of osteoclast with a greater number of nuclei were detected in the tibiae for Zr60. This research demonstrated that the new bone microarchitecture in contact with Zr60 is able to improve the early stages of the osseointegration process and consequently the primary stability of implants which is a crucial factor to reduce recovery time for patients.
Palabras clave: OSSEOINTEGRATION , ZIRCONIUM IMPLANTS , ANODIZATION , HISTOLOGY , HISTOMORPHOMETRY
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)
Identificadores
URI: http://hdl.handle.net/11336/130054
URL: http://link.springer.com/10.1007/s40204-019-00124-0
DOI: https://doi.org/10.1007/s40204-019-00124-0
Colecciones
Articulos(CCT - CORDOBA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA
Citación
Tano de la Hoz, María Florencia; Katunar, Maria Rosa; Gonzalez, Ariel; Gomez Sanchez, Andrea Valeria; Díaz, Alcira Ofelia; et al.; Effect of anodized zirconium implants on early osseointegration process in adult rats: a histological and histomorphometric study; Springer; Progress in Biomaterial; 8; 4; 22-11-2019; 249-260
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