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dc.contributor.author
García, Adolfo Martín
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dc.contributor.author
DeLeon, Jessica
dc.contributor.author
Tee, Boon Lead
dc.contributor.other
Dela Salla, Sergio
dc.date.available
2021-04-06T17:22:50Z
dc.date.issued
2020
dc.identifier.citation
García, Adolfo Martín; DeLeon, Jessica; Tee, Boon Lead; Neurodegenerative disorders of language and speech: Non-language-dominant diseases; Elsevier; 2020; 1-15
dc.identifier.isbn
978-0-12-809324-5
dc.identifier.uri
http://hdl.handle.net/11336/129455
dc.description.abstract
Speech and language networks span vast cortical and subcortical regions in the human brain, including putative perisylvian areas but extending well beyond them. Accordingly, relevant functions can be compromised by diverse neural disruptions even in non-language-dominant neurodegenerative diseases (nldNDs) i.e., conditions that are not primarily typified by speech or language dysfunction. The present chapter offers a systematic overview of this topic, focusing on the three most prevalent nldNDs (Alzheimers disease, Parkinsons disease, and behavioral variant frontotemporal dementia). In each case, we offer detailed descriptions of spared and impaired skills across speech/language levels (phonetics, phonology, lexicosemantics, morphosyntax, discourse-level processing) and multidimensional accounts of their core neural signatures (including patterns of brain atrophy and tractographic abnormalities as well as alterations in regional activation, functional connectivity, event-related potentials, and oscillatory modulations). Next, we offer a brief contrastive summary of the core patterns in each disease. Finally, we address the main implications of the evidence and the prime challenges facing the field in the immediate future. Briefly, this chapter provides a fine-grained, multimodal, transnosological view of speech and language disruptions beyond the diseases typically associated with them.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
LANGUAGE
dc.subject
ALZHEIMER'S DISEASE
dc.subject
PARKINSON'S DISEASE
dc.subject
BEHAVIORAL VARIANT FRONTOTEMPORAL DEMENTIA
dc.subject.classification
Lingüística
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dc.subject.classification
Lengua y Literatura
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dc.subject.classification
HUMANIDADES
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dc.subject.classification
Psicología
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dc.subject.classification
Psicología
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CIENCIAS SOCIALES
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dc.title
Neurodegenerative disorders of language and speech: Non-language-dominant diseases
dc.type
info:eu-repo/semantics/publishedVersion
dc.type
info:eu-repo/semantics/bookPart
dc.type
info:ar-repo/semantics/parte de libro
dc.date.updated
2021-03-15T15:48:39Z
dc.journal.pagination
1-15
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Educación Elemental y Especial; Argentina. Universidad de San Andrés; Argentina. University of California; Estados Unidos
dc.description.fil
Fil: DeLeon, Jessica. University of California; Estados Unidos
dc.description.fil
Fil: Tee, Boon Lead. University of California; Estados Unidos
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/B9780128196410000426?via%3Dihub
dc.conicet.paginas
1000
dc.source.titulo
Reference Module in Neuroscience and Biobehavioral Psychology
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