Artículo
CTX-M-14 β-lactamase-producing Citrobacter freundii isolated in Venezuela
Fecha de publicación:
05/2011
Editorial:
BioMed Central
Revista:
Annals of Clinical Microbiology and Antimicrobials
ISSN:
1476-0711
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
A clinical isolate of C. freundii with reduced susceptibility to extended-spectrum β-lactams from a woman with cystocele associated with recurrent urinary tract infection was analyzed. Susceptibility tests, double disk synergy tests (DDST) and enzymatic activity by the agar iodometric method suggested the presence of ESBLs. Conjugation experiments revealed the presence of a large conjugative plasmid (pLM07/20) with an exclusive FrepB replicon type (IncF/FIB). PCR analysis and sequencing confirmed the presence of the blaCTX-M-14 gene in the pLM07/20 from C. freundii.LM07/10. Although this is the first report of CTX-M-14 in Venezuela, we alert the medical community that future increase of these β-lactamases in our city could be due to dissemination of plasmids into bacterial populations.
Palabras clave:
Citrobacter Freundi
,
Ctx-M-14,
,
Plasmid
,
Frepb Replicon
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Identificadores
Colecciones
Articulos(OCA HOUSSAY)
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Citación
Millan, Beatriz; Ghiglione, Barbara; Diaz, Tulia; Gutkind, Gabriel Osvaldo; Araque, María; CTX-M-14 β-lactamase-producing Citrobacter freundii isolated in Venezuela; BioMed Central; Annals of Clinical Microbiology and Antimicrobials; 10; 22; 5-2011; 1-4
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