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dc.contributor.author Hirschler, Valeria
dc.contributor.author Meroño, Tomás
dc.contributor.author Maccallini, Gustavo
dc.contributor.author Gomez Rosso, Leonardo Adrián
dc.contributor.author Aranda, Claudio
dc.contributor.author Brites, Fernando Daniel
dc.date.available 2017-02-10T20:36:47Z
dc.date.issued 2011-01
dc.identifier.citation Hirschler, Valeria; Meroño, Tomás; Maccallini, Gustavo; Gomez Rosso, Leonardo Adrián; Aranda, Claudio; et al.; Impact of unhealthy lifestyle behaviors and obesity on CETP among adolescent boys; Instituto Mexicano del Seguro Social; Archives Of Medical Research (eletronico); 42; 1; 1-2011; 53-59
dc.identifier.issn 0188-4409
dc.identifier.uri http://hdl.handle.net/11336/12887
dc.description.abstract Background and Aims Cholesteryl ester transfer protein (CETP) has been proposed to be associated with high risk of cardiovascular disease. Increased CETP activity was previously reported in obese adults, although its association with lifestyle behaviors has not been assessed in healthy adolescents. We undertook this study to determine the association between CETP activity and overweight/obesity, insulin resistance markers, components of the metabolic syndrome and lifestyle behaviors in healthy adolescent males. Methods Data were collected from 164 adolescents from an amateur rugby club. Body mass index (BMI), blood pressure (BP), Tanner stages, lipids, glucose, insulin and CETP activity were measured. Questionnaires for daily intake of breakfast, sweet drinks, milk, and hours of TV watching were completed. Results About 26% of the adolescents were obese and 23% overweight. The prevalence of metabolic syndrome was 6.7%. CETP activity was higher in obese than in normal and overweight adolescents (174 ± 35, 141 ± 30, and 149 ± 38%/ml/min, respectively; p <0.001). Univariate correlations showed an inverse association between CETP and HDL-C (r = −0.43; p = 0.018) and positive ones with BMI (r = 0.38; p = 0.007), systolic BP (r = 0.20; p <0.01) triglycerides (r = 0.40; p = 0.001), LDL-C (r = 0.46; p <0.001), TV watching >2 h/day (r = 0.17; p 0.02), and milk intake >3 glasses/day (r = 0.16; p = 0.03). Multivariate analysis showed that triglycerides, LDL-C, HDL-C, TV watching >2 h/day, milk intake >3 glasses/day and BMI were significant independent predictors for CETP (R2 = 0.41). Conclusions Unhealthy lifestyle habits such as TV watching >2 h daily and milk intake higher than three glasses per day and the increase in BMI were shown to be closely associated with high CETP activity in apparently healthy adolescent males. Future longitudinal studies should be performed to confirm these findings.
dc.format application/pdf
dc.language.iso eng
dc.publisher Instituto Mexicano del Seguro Social
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject obesity
dc.subject adolescent boys
dc.subject CHOLESTERYL ESTER TRANSFER PROTEIN
dc.subject cardiovascular diseasse
dc.subject.classification Nutrición, Dietética
dc.subject.classification Ciencias de la Salud
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title Impact of unhealthy lifestyle behaviors and obesity on CETP among adolescent boys
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2017-02-09T18:23:00Z
dc.journal.volume 42
dc.journal.number 1
dc.journal.pagination 53-59
dc.journal.pais México
dc.description.fil Fil: Hirschler, Valeria. Hospital General de Agudos "Carlos G. Durand"; Argentina
dc.description.fil Fil: Meroño, Tomás. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
dc.description.fil Fil: Maccallini, Gustavo. Hospital General de Agudos "Carlos G. Durand"; Argentina
dc.description.fil Fil: Gomez Rosso, Leonardo Adrián. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
dc.description.fil Fil: Aranda, Claudio. Hospital General de Agudos "Carlos G. Durand"; Argentina
dc.description.fil Fil: Brites, Fernando Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
dc.journal.title Archives Of Medical Research (eletronico)
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://www.arcmedres.com/article/S0188-4409(10)00347-4/abstract
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.arcmed.2010.11.009
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0188440910003474


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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)