Artículo
Unraveling the gallol-driven assembly mechanism of thermoreversible supramolecular hydrogels inspired by ascidians
Wolfel Sánchez, Alexis
; Euti, Esteban
; Picchio, Matías Luis
; Romero, Marcelo Ricardo
; Galván Josa, Víctor Martín
; Martinelli, Marisa
; Minari, Roque Javier
; Alvarez Igarzabal, Cecilia Ines
Fecha de publicación:
10/2020
Editorial:
Royal Society of Chemistry
Revista:
Polymer Chemistry
ISSN:
1759-9954
e-ISSN:
1759-9962
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Polyphenols-based supramolecular hydrogels have recently attracted much attention as smart materials for applications in several technologies. Although great advances have been made in this field, there is a challenging need for creating new versatile materials that combine synthesis simplicity and suitable functional properties. In this work, inspired by the hydrogen bonding ability of pyrogallol-bearing proteins found in ascidians, we explored a small gallol analog, gallic acid (GA), as a dynamic crosslinker of poly(vinyl alcohol) (PVA). The fundamentals of the supramolecular assembly mechanism of PVA/GA hydrogels are studied for understanding the final properties of the obtained thermo-reversible hydrogels. The polymer deacetylation degree was a key factor to control the gelation kinetics, morphology, and properties of the supramolecular materials. Furthermore, the intercalation of GA molecules between PVA chains produced polymer crystals with a new spatial arrangement, modifying the elastic modulus of the supramolecular network and increasing its stability in water. With remarkable fast gelation ability, ascidian-inspired PVA-GA hydrogels may provide a promising platform for a wide range of biomedical applications including topical drug delivery of therapeutic proteins, wearable electronic devices, and 3D printing.
Palabras clave:
POLY VINYL ALCOHOL
,
PHENOLIC COMPONENTS
,
SUPRAMOLECULAR STRUCTURE
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Articulos(INTEC)
Articulos de INST.DE DES.TECNOL.PARA LA IND.QUIMICA (I)
Articulos de INST.DE DES.TECNOL.PARA LA IND.QUIMICA (I)
Citación
Wolfel Sánchez, Alexis; Euti, Esteban; Picchio, Matías Luis; Romero, Marcelo Ricardo; Galván Josa, Víctor Martín; et al.; Unraveling the gallol-driven assembly mechanism of thermoreversible supramolecular hydrogels inspired by ascidians; Royal Society of Chemistry; Polymer Chemistry; 11; 45; 10-2020; 7185-7198
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