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dc.contributor.author
Sabio, Germán
dc.contributor.author
Quesada Allue, Luis Alberto
dc.contributor.author
Pérez, Martín Mariano
dc.date.available
2017-02-07T20:41:28Z
dc.date.issued
2011-03
dc.identifier.citation
Sabio, Germán; Quesada Allue, Luis Alberto; Pérez, Martín Mariano; NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster; University of Oklahoma; Drosophila Information Service; 94; 3-2011; 100-104
dc.identifier.issn
0070-7333
dc.identifier.uri
http://hdl.handle.net/11336/12695
dc.description.abstract
Drosophila melanogaster genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
University of Oklahoma
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Catecholamines
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Neurotransmitters
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Insect Brain
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Insect Epidermis
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Bioquímica y Biología Molecular
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-02-07T13:52:47Z
dc.journal.volume
94
dc.journal.pagination
100-104
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Oklahoma
dc.description.fil
Fil: Sabio, Germán. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
dc.description.fil
Fil: Quesada Allue, Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
dc.description.fil
Fil: Pérez, Martín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
dc.journal.title
Drosophila Information Service
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.ou.edu/journals/dis/DIS94/Sabio%20100.pdf


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