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dc.contributor.author
Stivala, Maria Gilda
dc.contributor.author
Villecco, Margarita B.
dc.contributor.author
Fanzone, Martín
dc.contributor.author
Jofré, Viviana
dc.contributor.author
Rodriguez Vaquero, Maria Jose
dc.contributor.author
Aredes Fernández, Pedro Adrián
dc.date.available
2017-02-06T21:45:43Z
dc.date.issued
2014-01
dc.identifier.citation
Stivala, Maria Gilda; Villecco, Margarita B.; Fanzone, Martín; Jofré, Viviana; Rodriguez Vaquero, Maria Jose; et al.; Characterization, antibacterial and biological activities of phenolic fraction of argentinean red wines; Bentham Science Publishers; The Open Conference Proceedings Journal; 5; 1-2014; 29-37
dc.identifier.issn
2210-2892
dc.identifier.uri
http://hdl.handle.net/11336/12591
dc.description.abstract
For the first time, the qualitative and quantitative characterization of phenolic compounds of lower molecular weight fraction (LMF) were evaluated in commercial Cabernet Sauvignon (CS) and Tannat (T) wines varieties produced in Cafayate, Argentine. The antimicrobial activity against Pediococcus pentosaceus 12p, spoilage wine bacteria as well as the “in vitro” antioxidant and antihypertensive activities were also evaluated. The composition of LMF obtained by liquidliquid extraction with ethyl acetate, determined by HPLC-DAD, showed a total content of phenolic compounds of 229.4 and 311.1 mg L-1 for CS and T wines respectively. Synthetic like-wine media (SWM), pH 4.5 supplemented with LMF at identical concentration of the wine (1X), four (4X) and eight times concentrated (8X), was inoculated with P. pentosaceus 12p at 107CFU mL-1. Samples were collected at the beginning and final incubation time to determine cell viability in MRS-agar medium and the damage of the cell membrane integrity by electron microscopy observation. In the presence of LMF at 1X concentration, both fractions diminish growth parameters without cellular damage. In the presence of LMF of CS and T wine varieties four and eight times concentrated, cellular death of the microorganism as well as plasmatic membrane disruption was observed. The LMF of both wines analyzed in this study have high antioxidant, radical scavenging and antihypertensive activity. The use of phenolic compounds as potential antimicrobial agents could be an effective additive to controll wine spoilage bacteria, adding on wines beneficial properties to human health.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Bentham Science Publishers
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Antihypertensive Activity
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Antimicrobial Activity
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Antioxidant Activity
dc.subject
Pediococcus Pentosaceus
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Phenolic Compounds
dc.subject
Wine
dc.subject.classification
Biotecnología Agrícola y Biotecnología Alimentaria
dc.subject.classification
Biotecnología Agropecuaria
dc.subject.classification
CIENCIAS AGRÍCOLAS
dc.title
Characterization, antibacterial and biological activities of phenolic fraction of argentinean red wines
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-02-03T14:03:55Z
dc.journal.volume
5
dc.journal.pagination
29-37
dc.journal.pais
Emiratos Árabes Unidos
dc.journal.ciudad
Sharjah
dc.description.fil
Fil: Stivala, Maria Gilda. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Villecco, Margarita B.. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
dc.description.fil
Fil: Fanzone, Martín. Instituto Nacional de Tecnologia Agropecuaria. Centro Reg.cuyo Mendoza-san Juan. Estacion Exptal.agrop.mendoza. Laboratorio de Aromas y Sustancias Naturales; Argentina
dc.description.fil
Fil: Jofré, Viviana. Instituto Nacional de Tecnologia Agropecuaria. Centro Reg.cuyo Mendoza-san Juan. Estacion Exptal.agrop.mendoza. Laboratorio de Aromas y Sustancias Naturales; Argentina
dc.description.fil
Fil: Rodriguez Vaquero, Maria Jose. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Aredes Fernández, Pedro Adrián. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
The Open Conference Proceedings Journal
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/2210289201405030029
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://benthamopen.com/ABSTRACT/TOPROCJ-5-2-29


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