Artículo
The action of blood serum of the dog in a condition of tetania parathyreopriva on voluntary muscular tissue compared with that of normal serum
Fecha de publicación:
1919
Editorial:
The Physiological Society
Revista:
Quarterly Journal Of Experimental Physiology
ISSN:
0958-0670
Idioma:
Inglés
Volumen:
XII
Número:
2
Páginas:
111-114
Subtipo:
Artículo científico
Financiación:
Fundacion Williams.;
Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental;
Consejo Nacional de Investigaciones Científicas y Técnicas;
Nombre del Proyecto:
Proyecto Houssay y Leloir
Clasificación temática:
Resumen
In a recent paper G. M. Wishart gives the results of an attempt to obtain a qualitative estimation of the guanidin in blood by immersing frog muscles in serum. He found that, of six cases observed, the serum of three dogs which had been subjected to parathyroidectomy produced tremors in the muscles of the frog: whereas in three other cases there were no tremors. In some there was prolongation of the normal contraction-an effect similar to that produced by guanidin alone. The serum of a cat affected by tetania parathyreopriva also caused tremors in frog muscle: the serum of normal animals (six dogs and four cats) always proved inactive. The conclusion he draws is that " in certain cases the serum of parathyroidectomnised dogs and cats acts upon the muscles of the frog in the same way as do dilute solutions of guanidin and methylguanidin. But the variations in the susceptibility of the muscles of different frogs renders this biological test unreliable.
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Recursos continuos (Bernardo Alberto Houssay)
Recursos continuos (Bernardo Alberto Houssay)
Recursos continuos (Bernardo Alberto Houssay)
Citación
Houssay, Bernardo Alberto; The action of blood serum of the dog in a condition of tetania parathyreopriva on voluntary muscular tissue compared with that of normal serum; The Physiological Society; Quarterly Journal Of Experimental Physiology; XII; 2; 1919; 111-114
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