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dc.contributor.author
Tabesh, Maryam
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dc.contributor.author
Magliano, Dianna J.
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Tanamas, Stephanie K.
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Surmont, Filip
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Bahendeka, Silver
dc.contributor.author
Chiang, Chern En
dc.contributor.author
Elgart, Jorge Federico
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Gagliardino, Juan Jose
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Kalra, Sanjay
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Krishnamoorthy, Satheesh
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Luk, Andrea
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Maegawa, Hiroshi
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Motala, Ayesha A.
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Pirie, Fraser
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Ramachandran, Ambady
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Tayeb, Khaled
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Vikulova, Olga
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Wong, Jencia
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Shaw, Jonathan E.
dc.date.available
2021-01-12T13:19:47Z
dc.date.issued
2019-04-08
dc.identifier.citation
Tabesh, Maryam; Magliano, Dianna J.; Tanamas, Stephanie K.; Surmont, Filip; Bahendeka, Silver; et al.; Diabetes management and treatment approaches outside of North America and West Europe in 2006 and 2015; Springer; Acta Diabetológica; 56; 8; 8-4-2019; 889-897
dc.identifier.issn
0940-5429
dc.identifier.uri
http://hdl.handle.net/11336/122454
dc.description.abstract
Aims The impact of introducing new classes of glucose-lowering medication (GLM) on diabetes management remains unclear, especially outside North America and Western Europe. Therefore, we aimed to analyse trends in glycaemic control and the usage of new and old GLMs in people with type 2 diabetes from 2006 to 2015. Methods Summary data from clinical services from nine countries outside North America and Western Europe were collected and pooled for statistical analysis. Each site summarized individual-level data from out-patient medical records for 2006 and 2015. Data included: demographics; HbA1c and fasting plasma glucose levels; and the proportions of patients taking GLM as monotherapy, combination therapy and/or insulin. Results Between 2006 and 2015, glycaemic control remained stable, although body mass index and duration of diabetes increased in most sites. The proportion of people on GLM increased, and the therapeutic regimens became more complex. There were increases in the use of insulin and triple therapy in most sites, while monotherapy, particularly in relation to sulphonylureas, decreased. Despite the introduction of new GLMs, such as DPP-4 inhibitors, insulin use increased over time. Conclusions There was no clear evidence that the use of new classes of GLMs was associated with improvements in glycaemic control or reduced the reliance on insulin. These findings were consistent across a range of economic and geographic settings.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
DIABETES MELLITUS
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DISEASE MANAGEMENT
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GLYCATED HAEMOGLOBIN
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HYPOGLYCAEMIC AGENTS
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THERAPEUTICS
dc.subject.classification
Endocrinología y Metabolismo
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Diabetes management and treatment approaches outside of North America and West Europe in 2006 and 2015
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-11-20T17:17:33Z
dc.journal.volume
56
dc.journal.number
8
dc.journal.pagination
889-897
dc.journal.pais
Alemania
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dc.journal.ciudad
Berlin
dc.description.fil
Fil: Tabesh, Maryam. Monash University; Australia. Baker Heart and Diabetes Institute; Australia
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Fil: Magliano, Dianna J.. Monash University; Australia. Baker Heart and Diabetes Institute; Australia
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Fil: Tanamas, Stephanie K.. Baker Heart and Diabetes Institute; Australia
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Fil: Surmont, Filip. Astrazeneca; Reino Unido
dc.description.fil
Fil: Bahendeka, Silver. Uganda Martyrs University; Uganda. St. Francis Hospital Nsambya; Uganda
dc.description.fil
Fil: Chiang, Chern En. Taipei Veterans General Hospital; China
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Fil: Elgart, Jorge Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Endocrinología Experimental y Aplicada. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Endocrinología Experimental y Aplicada; Argentina
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Fil: Gagliardino, Juan Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Endocrinología Experimental y Aplicada. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Endocrinología Experimental y Aplicada; Argentina
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Fil: Kalra, Sanjay. Bharti Research Institute of Diabetes and Endocrinology; India
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Fil: Krishnamoorthy, Satheesh. Dr A Ramachandran’s Diabetes Hospitals; India
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Fil: Luk, Andrea. Prince of Wales Hospital Hong Kong; Hong Kong
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Fil: Maegawa, Hiroshi. Shiga University of Medical Science; Japón
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Fil: Motala, Ayesha A.. University of KwaZulu Natal; Sudáfrica
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Fil: Pirie, Fraser. University of KwaZulu Natal; Sudáfrica
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Fil: Ramachandran, Ambady. Dr A Ramachandran’s Diabetes Hospitals; India
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Fil: Tayeb, Khaled. Diabetes Center at Al-Noor Specialist Hospital; Arabia Saudita
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Fil: Vikulova, Olga. FGBU “Endocrinology Research Center” Ministry of Health; Rusia
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Fil: Wong, Jencia. University of Sydney; Australia
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Fil: Shaw, Jonathan E.. Baker Heart and Diabetes Institute; Australia. Monash University; Australia
dc.journal.title
Acta Diabetológica
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s00592-018-01284-4
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s00592-018-01284-4
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