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dc.contributor.author
Elguero, María Eugenia
dc.contributor.author
Nudel, Berta Clara
dc.contributor.author
Nusblat, Alejandro David
dc.date.available
2021-01-06T13:22:45Z
dc.date.issued
2019-09
dc.identifier.citation
Elguero, María Eugenia; Nudel, Berta Clara; Nusblat, Alejandro David; Biotechnology in ciliates: an overview; Taylor & Francis; Critical Reviews In Biotechnology; 39; 2; 9-2019; 220-234
dc.identifier.issn
0738-8551
dc.identifier.uri
http://hdl.handle.net/11336/121580
dc.description.abstract
Since their description and classification in the 19th century, ciliates have played an important role in science, leading to several fundamental discoveries in the areas of cellular and molecular biology. During the last decades, with the emergence of biotechnology, many new developments are also coming to light. In this review, we describe a range of applications in which ciliates have found a niche, ranging from the production of a vast array of proteins, lipids, metabolites, and antigens to their use in toxicity screening, biocontrol, bioremediation, and biotransformation of substrates into more valuable products. We highlight the benefits and drawbacks of their use in biotechnology, the latest developments in large-scale culture and state-of-the-art molecular-genetic techniques, as well as the estimations on the exploitation areas with better potential, i.e., the production of complex membrane proteins, and those less interesting or with less chances of success.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Taylor & Francis
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Ciliates; biotechnology; large-scale culture;
dc.subject
membrane proteins;
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strain development;
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toxicity
dc.subject.classification
Biología Celular, Microbiología
dc.subject.classification
Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Biotechnology in ciliates: an overview
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-12-17T19:15:22Z
dc.identifier.eissn
1549-7801
dc.journal.volume
39
dc.journal.number
2
dc.journal.pagination
220-234
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Londres
dc.description.fil
Fil: Elguero, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Nanobiotecnología. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Nanobiotecnología; Argentina
dc.description.fil
Fil: Nudel, Berta Clara. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Nanobiotecnología. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Nanobiotecnología; Argentina
dc.description.fil
Fil: Nusblat, Alejandro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Nanobiotecnología. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Nanobiotecnología; Argentina
dc.journal.title
Critical Reviews In Biotechnology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/07388551.2018.1530188
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/07388551.2018.1530188
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