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dc.contributor.author
Fernandez, Ariel  
dc.date.available
2021-01-05T16:51:57Z  
dc.date.issued
2020-12  
dc.identifier.citation
Fernandez, Ariel; Defusing SARS-CoV-2: Emergency Brakes in a Vaccine Failure Scenario; American Chemical Society Inc; ACS Pharmacology and Translational Science; 3; 12-2020; 1425-1426  
dc.identifier.issn
2575-9108  
dc.identifier.uri
http://hdl.handle.net/11336/121495  
dc.description.abstract
Deactivation of primed SARS-CoV-2 prior to cell entry constitutes an emergency brake in COVID-19 infection if vaccine-induced antibodies fail to block recognition of the human angiotensin-converting enzyme 2 (hACE2) receptor. The timing and locus for the therapeutic intervention are dictated by the cell entry mechanism and by the selective advantage of the dominant D614G mutation.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
American Chemical Society Inc  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
SARS-CoV-2  
dc.subject
COVID-19  
dc.subject
antibody  
dc.subject
virus transmissibility  
dc.subject.classification
Biotecnología relacionada con la Salud  
dc.subject.classification
Biotecnología de la Salud  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Defusing SARS-CoV-2: Emergency Brakes in a Vaccine Failure Scenario  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2021-01-05T14:26:03Z  
dc.journal.volume
3  
dc.journal.pagination
1425-1426  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Fernandez, Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina  
dc.journal.title
ACS Pharmacology and Translational Science  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acsptsci.0c00152  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1021/acsptsci.0c00152  

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