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dc.contributor.author
Vaschetto, Luis Maria Benjamin
dc.contributor.author
Ortiz, Natalia
dc.date.available
2020-12-16T21:48:54Z
dc.date.issued
2019-01-24
dc.identifier.citation
Vaschetto, Luis Maria Benjamin; Ortiz, Natalia; The role of sequence duplication in transcriptional regulation and genome evolution; Bentham Science Publishers; Current Genomics; 20; 6; 24-1-2019; 405-408
dc.identifier.issn
1389-2029
dc.identifier.uri
http://hdl.handle.net/11336/120660
dc.description.abstract
Sequence duplication is nowadays recognized as an important mechanism that underlies the evolution of eukaryote genomes, being indeed one of the most powerful strategies for the generation of adaptive diversity by modulating transcriptional activity. The evolutionary novelties simultaneously associated with sequence duplication and differential gene expression can be collectively referred to as duplication-mediated transcriptional regulation. In the last years, evidence has emerged supporting the idea that sequence duplication and functionalization represent important evolutionary strategies acting at the genome level, and both coding and non-coding sequences have been found to be targets of such events. Moreover, it has been proposed that deleterious effects of sequence duplication might be potentially silenced by endogenous cell machinery (i.e., RNA interference, epigenetic repressive marks, etc). Along these lines, our aim is to highlight the role of sequence duplication on transcriptional activity and the importance of both in genome evolution.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Bentham Science Publishers
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
GENE DUPLICATION
dc.subject
GENE EXPRESSION
dc.subject
GENOME EVOLUTION
dc.subject
SEQUENCE DUPLICATION
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TRANSCRIPTIONAL REGULATION
dc.subject
TRANSPOSABLE ELEMENTS
dc.subject.classification
Genética y Herencia
dc.subject.classification
Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
The role of sequence duplication in transcriptional regulation and genome evolution
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-11-19T21:13:17Z
dc.journal.volume
20
dc.journal.number
6
dc.journal.pagination
405-408
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Oak Park
dc.description.fil
Fil: Vaschetto, Luis Maria Benjamin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Diversidad y Ecología Animal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Diversidad y Ecología Animal; Argentina
dc.description.fil
Fil: Ortiz, Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Diversidad y Ecología Animal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Diversidad y Ecología Animal; Argentina
dc.journal.title
Current Genomics
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/170867/article
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/1389202920666190320140721
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235390/
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