Repositorio Institucional
Repositorio Institucional
CONICET Digital
  • Inicio
  • EXPLORAR
    • AUTORES
    • DISCIPLINAS
    • COMUNIDADES
  • Estadísticas
  • Novedades
    • Noticias
    • Boletines
  • Ayuda
  • Acerca de
    • CONICET Digital
    • Equipo
    • Red Federal
JavaScript is disabled for your browser. Some features of this site may not work without it.
  • INFORMACIÓN GENERAL
  • RESUMEN
  • ESTADISTICAS
 
Artículo

ODF1, sperm flagelar protein is expressed in kidney collecting ducts of rats

Cabrillana, María EugeniaIcon ; Bocanegra, María VictoriaIcon ; Monclus, Maria de Los AngelesIcon ; Saez Lancellotti, Tania Emilce EstefaniaIcon ; Simón, Layla YamilaIcon ; Funes, Abi KareninaIcon ; Colombo, Regina LucíaIcon ; Ruiz Estrabón, Martín Andres; Vincenti, Amanda EdithIcon ; Oliva Virgili, Rafael; Fornes, Miguel WalterIcon
Fecha de publicación: 12/2019
Editorial: Elsevier
Revista: Heliyon
ISSN: 2405-8440
e-ISSN: E02932
Idioma: Inglés
Tipo de recurso: Artículo publicado

Resumen

ODF1 has been described as an exclusively expressed testicular protein and is located in the outer dense fibersalong the sperm tail. ODF1 has been involved in the sperm motility and in the development of the flagellum, butthe function of ODF1 is not already clear. Other ODF proteins, such as ODF2 have been characterized in othertissues like the basal body of the kidney primary cilium, but so far only the mRNA of ODF1 has been described inother tissues. These observations let us to hypothesize that the expression of the protein ODF1 could not belimited to the testis. Therefore, in the present work we proposed to evaluate if the ODF1 protein could also bepresent in tissues other than the testis. Here we demonstrated through western blot, immunofluorescence, and RTPCR techniques that the protein and mRNA of ODF1 have been identified in the rat kidney. Finally, the presenceof ODF1 in kidney has also been confirmed through proteomic analysis using mass spectrometry. The resultsderived from these different complementary approaches indicate that, to our knowledge and for the first time,ODF1 is demonstrated to be present in an additional organ different to testis. This results raise new questionsabout potential other functions and locations of the ODF1 protein.
Palabras clave: CELL BIOLOGY , COLLECTING DUCT , ODF1 , PROTEINS , PROTEOMIC , REPRODUCTIVE SYSTEM
Ver el registro completo
 
Archivos asociados
Tamaño: 2.027Mb
Formato: PDF
.
Solicitar
Licencia
info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/119667
URL: https://www.sciencedirect.com/science/article/pii/S2405844019365910
DOI: http://dx.doi.org/10.1016/j.heliyon.2019.e02932
Colecciones
Articulos(IHEM) [262]
Articulos de INST. HISTOLOGIA Y EMBRIOLOGIA DE MEND DR.M.BURGOS
Articulos(IMBECU) [384]
Articulos de INST. DE MEDICINA Y BIO. EXP. DE CUYO
Citación
Cabrillana, María Eugenia; Bocanegra, María Victoria; Monclus, Maria de Los Angeles; Saez Lancellotti, Tania Emilce Estefania; Simón, Layla Yamila; et al.; ODF1, sperm flagelar protein is expressed in kidney collecting ducts of rats; Elsevier; Heliyon; 5; 12; 12-2019; 1-8
Compartir
Altmétricas
 
Estadísticas
Visualizaciones: 16
Descargas: 4

Enviar por e-mail
Separar cada destinatario (hasta 5) con punto y coma.
  • Facebook
  • Twitter
  • Instagram
  • YouTube
  • Sound Cloud

Los contenidos del CONICET están licenciados bajo Creative Commons Reconocimiento 2.5 Argentina License

Ministerio
https://www.conicet.gov.ar/ - CONICET

Inicio

Explorar

  • Autores
  • Disciplinas
  • Comunidades

Estadísticas

Novedades

  • Noticias
  • Boletines

Ayuda

Acerca de

  • CONICET Digital
  • Equipo
  • Red Federal
Godoy Cruz 2290 (C1425FQB) CABA – República Argentina – Tel: +5411 4899-5400 repositorio@conicet.gov.ar
TÉRMINOS Y CONDICIONES