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dc.contributor.author
Tomson, Torbjörn  
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Battino, Dina  
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Bromley, Rebecca  
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Kochen, Sara Silvia  
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Meador, Kimford  
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Pennell, Page  
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Thomas, Sanjeev V.  
dc.date.available
2020-11-26T13:55:23Z  
dc.date.issued
2019-12  
dc.identifier.citation
Tomson, Torbjörn; Battino, Dina; Bromley, Rebecca; Kochen, Sara Silvia; Meador, Kimford; et al.; Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy; International League Against Epilepsy; Epileptic Disorders; 21; 6; 12-2019; 497-517  
dc.identifier.issn
1950-6945  
dc.identifier.uri
http://hdl.handle.net/11336/119061  
dc.description.abstract
The risks associated with use of antiepileptic drugs during pregnancy are a major concern for all women with epilepsy with childbearing potential. These risks have to be balanced against foetal and maternal risks associated with uncontrolled seizures. This report from the International League Against Epilepsy Task Force on Women and Pregnancy aims to provide a summary of relevant data on these risks as a basis for expert opinion recommendations for the management of epilepsy in pregnancy. The report reviews data on maternal and foetal risks associated with seizures as well as teratogenic risks associated with antiepileptic drug exposure, including effects on intrauterine growth, major congenital malformations, and developmental and behavioural outcomes. The impact of pregnancy on seizure control and on the pharmacokinetics of antiepileptic drugs are also discussed. This information is used to discuss how treatment may be optimized before conception and further managed during pregnancy.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
International League Against Epilepsy  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-sa/2.5/ar/  
dc.subject
ANTIEPILEPTIC DRUGS  
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EPILEPSY  
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FOETAL RISKS  
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PREGNANCY  
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TERATOGENESIS  
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Neurología Clínica  
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Medicina Clínica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-11-19T21:56:14Z  
dc.journal.volume
21  
dc.journal.number
6  
dc.journal.pagination
497-517  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Tomson, Torbjörn. Karolinska University Hospital; Suecia  
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Fil: Battino, Dina. No especifíca;  
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Fil: Bromley, Rebecca. University of Manchester; Reino Unido  
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Fil: Kochen, Sara Silvia. Universidad Nacional Arturo Jauretche. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Provincia de Buenos Aires. Ministerio de Salud. Hospital Alta Complejidad en Red El Cruce Dr. Néstor Carlos Kirchner Samic. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos; Argentina  
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Fil: Meador, Kimford. University of Stanford; Estados Unidos  
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Fil: Pennell, Page. Brigham And Women's Hospital; Estados Unidos  
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Fil: Thomas, Sanjeev V.. Sree Chitra Tirunal Institute For Medical Sciences And Technology; India  
dc.journal.title
Epileptic Disorders  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.jle.com/fr/revues/epd/e-docs/management_of_epilepsy_in_pregnancy_a_report_from_the_international_league_against_epilepsy_task_force_on_women_and_pregnancy_315740/article.phtml  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1684/epd.2019.1105