Capítulo de Libro
Multifunctional scaffolds for bone tissue engineering and in situ drug delivery
Título del libro: Tissue engineering using ceramics and polymers
Mouriño, Viviana Silvia Lourdes
; Cattalini, Juan Pablo; Wei, L.; Boccaccini, A. R.; Lucangioli, Silvia Edith
Otros responsables:
Boccaccini, Aldo R.
Fecha de publicación:
2013
Editorial:
Woodhead Publishing
ISBN:
978-0-85709-712-5
Idioma:
Inglés
Clasificación temática:
Resumen
This chapter provides an overview about the development of bone tissue engineering scaffolds with capability for the controlled delivery of therapeutic drugs. Typical drugs considered include gentamicin and other antibiotics generally used to combat osteomyelitis as well as anti-inflammatory drugs and bisphosphonates. Special attention has been given to the technology used for controlling the release of the loaded drugs. A detailed summary of drugs included in bone tissue scaffolds is presented and the several approaches developed to combine organic and inorganic biomaterials in composites for drug delivery systems are discussed. The remaining challenges in the field are summarized suggesting also future research directions.
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Citación
Mouriño, Viviana Silvia Lourdes; Cattalini, Juan Pablo; Wei, L.; Boccaccini, A. R.; Lucangioli, Silvia Edith; Multifunctional scaffolds for bone tissue engineering and in situ drug delivery; Woodhead Publishing; 2013; 648-674
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