Artículo

Design and microwave-assisted synthesis of aza-resveratrol analogues with potent cholinesterase inhibition

Biscussi, BrunellaIcon ; Richmond, VictoriaIcon ; Baier, Carlos JavierIcon ; Arroyo Mañez, PauIcon ; Murray, Ana PaulaIcon
Fecha de publicación: 09/2020
Editorial: Bentham Science Publishers
Revista: Cns & Neurological Disorders-drug Targets
ISSN: 1871-5273
e-ISSN: 1996-3181
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Currently approved Alzheimer’s disease medications mainly comprise acetylcholinesterase inhibitors. Many of these inhibitors are either natural compounds or synthetic molecules inspired in natural compounds. Hybrids molecules that can interact with different target sites of the enzyme could lead to the discovery of effective multitarget drugs.
Palabras clave: AZA-RESVERATROL ANALOGUES , CHOLINESTERASE INHIBITORS , ALZHEIMER’S DISEASE , RATIONAL DESIGN , MICROWAVE-ASSISTED SYNTHESIS , SH-SY5Y NEUROBLASTOMA CELLS , MOLECULAR MODELING
 
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/115995
URL: https://www.eurekaselect.com/185607/article
DOI: http://dx.doi.org/10.2174/1871527319666200905121536
Colecciones
Articulos(INBIOSUR)
Articulos de INSTITUTO DE CIENCIAS BIOLOGICAS Y BIOMEDICAS DEL SUR
Articulos(INQUISUR)
Articulos de INST.DE QUIMICA DEL SUR
Citación
Biscussi, Brunella; Richmond, Victoria; Baier, Carlos Javier; Arroyo Mañez, Pau; Murray, Ana Paula; Design and microwave-assisted synthesis of aza-resveratrol analogues with potent cholinesterase inhibition; Bentham Science Publishers; Cns & Neurological Disorders-drug Targets; 19; 9-2020; 1-12
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