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dc.contributor.author
Ceresole, Rita  
dc.contributor.author
Rosasco, María Ana  
dc.contributor.author
Segall, Adriana Ines  
dc.date.available
2020-09-28T17:47:00Z  
dc.date.issued
2009-01  
dc.identifier.citation
Ceresole, Rita; Rosasco, María Ana; Segall, Adriana Ines; HPLC assay for meprednisone in tablets; Taylor & Francis; Journal of Liquid Chromatography and Related Technologies; 32; 19; 1-2009; 2795-2804  
dc.identifier.issn
1082-6076  
dc.identifier.uri
http://hdl.handle.net/11336/115006  
dc.description.abstract
A high performance liquid chromatographic (HPLC) method is presented for the determination of meprednisone in the presence of its degradation products using a reverse phase C18 column at ambient temperature with mobile phase consisting of acetonitrile:0.04M dibasic sodium phosphate, pH adjusted to 7.0 (45:65, v/v). The flow rate was 1.3mL/min. Quantitation was achieved with UV detection at 245nm based on peak area. The method was developed and validated for the determination of meprednisone in tablets. The proposed method was validated for selectivity, linearity, accuracy, and robustness. The method was found to be suitable for the quality control of meprednisone in tablets as well as the stability indicating studies.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Taylor & Francis  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
ASSAY  
dc.subject
HPLC  
dc.subject
MEPREDNISONE  
dc.subject
STABILITY INDICATING METHOD  
dc.subject.classification
Otras Ciencias Médicas  
dc.subject.classification
Otras Ciencias Médicas  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
HPLC assay for meprednisone in tablets  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-09-08T14:06:36Z  
dc.journal.volume
32  
dc.journal.number
19  
dc.journal.pagination
2795-2804  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Ceresole, Rita. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Laboratorio de Control de Calidad de Medicamentos; Argentina  
dc.description.fil
Fil: Rosasco, María Ana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Laboratorio de Control de Calidad de Medicamentos; Argentina  
dc.description.fil
Fil: Segall, Adriana Ines. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Laboratorio de Control de Calidad de Medicamentos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina  
dc.journal.title
Journal of Liquid Chromatography and Related Technologies  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.1080/10826070903288144  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1080/10826070903288144  

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