Tyrosine phosphatases in steroidogenic cells: Regulation and function

In adrenocortical and Leydig cells PKA activation by trophic hormones increases the activity of protein tyrosine phosphatases and also induces the expression of MAP kinase phosphatase 1 (MKP-1), a dual activity protein phosphatase (serine/threonine and tyrosine). This work summarizes the knowledge on the regulation and the role played by cAMP-activated tyrosine phosphatases as well as MKP-1 in the hormonal activation of the acute and chronic phases of steroidogenesis.

Palabras clave: phosphatase , MAPK , PTP , adrenal

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Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)

Identificadores

URI: http://hdl.handle.net/11336/113521

URL: https://www.sciencedirect.com/science/article/abs/pii/S0303720706005648

DOI: https://doi.org/10.1016/j.mce.2006.12.009

Colecciones

Articulos(INBIOMED)
Articulos de INSTITUTO DE INVESTIGACIONES BIOMEDICAS

Articulos(OCA HOUSSAY)
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY

Citación

Gorostizaga, Alejandra Beatriz; Cornejo Maciel, Maria Fabiana; Brion, Laura; Maloberti, Paula Mariana; Podesta, Ernesto Jorge; et al.; Tyrosine phosphatases in steroidogenic cells: Regulation and function; Elsevier Ireland; Molecular and Cellular Endocrinology; 265-266; 2-2007; 131-137

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