Fitoquimica y bioactividad de Chiliotrichum diffusum (Asteraceae) una especie nativa de la Patagonia Andina

Abstract

“Phytochemistry and Bioactivity of Chiliotrichum diffusum (Astereaceae), a Native Specie from the Andean Patagonian”. Chiliotrichum diffusum (Asteraceae), “mata negra”, inhabits the south of Argentina. Ethnic rituals and medicinal uses have been described for this species. Flavonoids, tannins, carbohydrates, proteins, anthraquinones, saponins, cyanoglycosides and steroids were detected in the aerial parts. The analysis of the flavonoid fraction demonstrated an important structural variability. The principal flavonoid groups detected were flavones and flavonol 7-O-glycosides, dihydroflavonols and isoflavones. The alcoholic extract and their fractions showed activity against Artemia salina cytotoxicity bioassay. The antimicrobial activity was moderate against Staphylococcus aureus.