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dc.contributor.author
Torralva, Teresa
dc.contributor.author
Gleichgerrcht, Ezequiel
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Torres Ardila, María Juliana
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Roca, María
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Manes, Facundo Francisco
dc.date.available
2020-08-25T17:29:10Z
dc.date.issued
2015-06
dc.identifier.citation
Torralva, Teresa; Gleichgerrcht, Ezequiel; Torres Ardila, María Juliana; Roca, María; Manes, Facundo Francisco; Differential Cognitive and Affective Theory of Mind Abilities at Mild and Moderate Stages of Behavioral Variant Frontotemporal Dementia; Lippincott Williams; Cognitive and Behavioral Neurology; 28; 6-2015; 63-70
dc.identifier.issn
1543-3633
dc.identifier.uri
http://hdl.handle.net/11336/112361
dc.description.abstract
To study the affective and cognitive components of theory of mind (ToM) performance in patients with behavioral variant frontotemporal dementia (bvFTD), focusing on differential impairment at mild and moderate disease stages.ToM, a central capacity for appropriate social behavior, is critically impaired in patients with bvFTD, even early in the disease. No previous study has explored how the cognitive and affective components of ToM may relate differentially to disease severity.METHODS:We assessed 40 patients with an established diagnosis of bvFTD and 18 healthy controls, using a complete neuropsychological battery that featured executive function and ToM tasks. We used patients´ Clinical Dementia Rating scores to classify them as having either mild or moderate bvFTD.RESULTS:Both groups of patients showed deficits in the affective and cognitive components of ToM relative to the controls. The patients with mild bvFTD outperformed the group with moderate bvFTD in cognitive ToM capacities; however, affective ToM was equally impaired in both bvFTD groups. The cognitive, but not the affective, component of ToM correlated with performance on the executive function tests.CONCLUSIONS:Our results suggest that affective ToM is markedly diminished even during the initial stages of bvFTD; as the disease progresses, deficits in cognitive ToM become more prominent. These findings may relate to the pattern of cortical atrophy described for bvFTD. We also found significant correlations between the cognitive component of ToM and executive functions.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Lippincott Williams
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BEHAVIORAL VARIANT FRONTOTEMPORAL DEMENTIA
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THEORY OF MIND
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EXECUTIVE FUNCTIONS
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SOCIAL COGNITION
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FRONTAL LOBES
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Neurociencias
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Differential Cognitive and Affective Theory of Mind Abilities at Mild and Moderate Stages of Behavioral Variant Frontotemporal Dementia
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-08-25T15:18:16Z
dc.journal.volume
28
dc.journal.pagination
63-70
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Philadelphia
dc.description.fil
Fil: Torralva, Teresa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Favaloro; Argentina. Macquarie University; Australia
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Fil: Gleichgerrcht, Ezequiel. The Medical University of South Carolina; Estados Unidos
dc.description.fil
Fil: Torres Ardila, María Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
dc.description.fil
Fil: Roca, María. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
dc.description.fil
Fil: Manes, Facundo Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
dc.journal.title
Cognitive and Behavioral Neurology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://pubmed.ncbi.nlm.nih.gov/26102996/
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1097/WNN.0000000000000053.
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